Literature DB >> 8933161

The role of macrophages in chronic arthritis.

W B van den Berg1, P L van Lent.   

Abstract

Rheumatoid arthritis is characterized by a mononuclear infiltrate in the synovial tissue of the affected joints, considerable thickening of the synovial lining layer and concomitant destruction of cartilage and bone. Macrophages probably play a central role and the contribution of the synovial lining macrophages is addressed in studies in experimental murine arthritis models. Emphasis is given to the involvement in arthritis expression and cartilage destruction. The role of TNF-alpha and IL-1, and the modulatory cytokines IL-4/ IL-10 is briefly discussed.

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Year:  1996        PMID： 8933161     DOI： 10.1016/S0171-2985(96)80026-X

Source DB:  PubMed          Journal:  Immunobiology        ISSN： 0171-2985            Impact factor:   3.144


  15 in total

1.  ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice.

Authors:  J L Smith; A E Schaffner; J K Hofmeister; M Hartman; G Wei; D Forsthoefel; D A Hume; M C Ostrowski
Journal:  Mol Cell Biol       Date:  2000-11       Impact factor: 4.272

Review 2.  Dendritic cells, Fc{gamma} receptors, and Toll-like receptors: potential allies in the battle against rheumatoid arthritis.

Authors:  T R D J Radstake; A W T van Lieshout; P L C M van Riel; W B van den Berg; G J Adema
Journal:  Ann Rheum Dis       Date:  2005-05-05       Impact factor: 19.103

3.  Glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, inhibits the progression of group B streptococcal arthritis.

Authors:  Luciana Tissi; Manuela Puliti; Francesco Bistoni; Paolo Mosci; Thomas R Kozel; Anna Vecchiarelli
Journal:  Infect Immun       Date:  2004-11       Impact factor: 3.441

4.  Circulating levels of the chemokine CCL18 but not CXCL16 are elevated and correlate with disease activity in rheumatoid arthritis.

Authors:  Antoine W T van Lieshout; Jaap Fransen; Marcel Flendrie; Agnes M M Eijsbouts; Frank H J van den Hoogen; Piet L C M van Riel; Timothy R D J Radstake
Journal:  Ann Rheum Dis       Date:  2007-03-09       Impact factor: 19.103

5.  Immunohistochemical study of lymphoid tissues in adjuvant arthritis (AA) by image analysis; relationship with synovial lesions.

Authors:  M Carol; C Pelegrí; C Castellote; A Franch; M Castell
Journal:  Clin Exp Immunol       Date:  2000-04       Impact factor: 4.330

6.  p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis.

Authors:  John C Scatizzi; Jack Hutcheson; Emily Bickel; James M Woods; Karolina Klosowska; Terry L Moore; G Kenneth Haines; Harris Perlman
Journal:  Am J Pathol       Date:  2006-05       Impact factor: 4.307

Review 7.  Targeted drug-delivery approaches by nanoparticulate carriers in the therapy of inflammatory diseases.

Authors:  Wiebke Ulbrich; Alf Lamprecht
Journal:  J R Soc Interface       Date:  2009-11-25       Impact factor: 4.118

8.  Photodynamic therapy using talaporfin sodium for synovial membrane from rheumatoid arthritis patients and collagen-induced arthritis rats.

Authors:  Eiji Torikai; Yasunori Kageyama; Eiji Kohno; Toru Hirano; Yukio Koide; Susumu Terakawa; Akira Nagano
Journal:  Clin Rheumatol       Date:  2007-12-08       Impact factor: 2.980

Review 9.  The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.

Authors:  Carla M Cuda; Richard M Pope; Harris Perlman
Journal:  Nat Rev Rheumatol       Date:  2016-08-23       Impact factor: 20.543

10.  Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis.

Authors:  J M Metselaar; W B van den Berg; A E M Holthuysen; M H M Wauben; G Storm; P L E M van Lent
Journal:  Ann Rheum Dis       Date:  2004-04       Impact factor: 19.103
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