| Literature DB >> 8931916 |
T Rabinowitz1, F R Frankenburg, F Centorrino, J Kando.
Abstract
This study examined the effect of clozapine on saliva flow rate. Unstimulated whole saliva was collected from 9 patients taking clozapine (dose range = 50-400 mg/day) and from 8 controls who had never used clozapine. There was no significant difference between the average saliva flow rates in the two groups (p > .10), nor was there significant correlation between saliva flow rate and daily clozapine dose (p > .10). Alternative explanations for observations or complaints of excessive salivation, drooling, or a choking feeling while taking clozapine are proposed.Entities:
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Year: 1996 PMID： 8931916 DOI： 10.1016/S0006-3223(96)89255-9
Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382