Cancer in hyperthyroidism.

The aim of the study was to determine the incidence of thyroid cancer in toxic goitre. Based on the material from 14,500 goitre surgeries, including 3,466 patients with toxic goitre, incidence of thyroid cancer, in relation to age and sex of the patients were determined. In 14,500 goitre surgeries, 12,887 women and 1,613 men (F:M 7.99:1), 639 (4.4%) cases of thyroid cancer were found. Among 3,466 patients with toxic goitre, thyroid cancer was found in 21 cases (0.6%)-20 females and 1 male, including 18 nodular toxic goitre and 3 Graves disease cases. The difference between the incidence of thyroid cancer in nontoxic and toxic goitre is statistically significant.