Literature DB >> 8931717

Isolation and structure elucidation of five new asterriquinones from Aspergillus, Humicola and Botryotrichum species.

U Mocek1, L Schultz, T Buchan, C Baek, L Fretto, J Nzerem, L Sehl, U Sinha.   

Abstract

Five new quinone pigments have been discovered from the fermentation broth of Aspergillus, Humicola and Botryotrichum species isolated from different soil samples. These compounds inhibit serine proteases of the coagulation pathway. Their structures which differ in the identity and position of a 5-carbon side chain on the indole moiety have been elucidated based on NMR and FAB-MS experiments.

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Year:  1996        PMID: 8931717     DOI: 10.7164/antibiotics.49.854

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Characterization of cyclo-acetoacetyl-L-tryptophan dimethylallyltransferase in cyclopiazonic acid biosynthesis: substrate promiscuity and site directed mutagenesis studies.

Authors:  Xinyu Liu; Christopher T Walsh
Journal:  Biochemistry       Date:  2009-11-24       Impact factor: 3.162

2.  Induction of cryptic metabolites of the endophytic fungus Trichocladium sp. through OSMAC and co-cultivation.

Authors:  Nam Michael Tran-Cong; Attila Mándi; Tibor Kurtán; Werner E G Müller; Rainer Kalscheuer; Wenhan Lin; Zhen Liu; Peter Proksch
Journal:  RSC Adv       Date:  2019-08-30       Impact factor: 4.036

  2 in total

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