Literature DB >> 8930538

Synergistic signals in the environment.

S F Arnold1, J A McLachlan.   

Abstract

Numerous endogenous signals (such as hormones and growth factors) or environmental signals (including chemicals or temperature) contribute to determining the overall biological response produced by cells. Some combinations of endogenous or environmental signals produce synergistic activity. This commentary examines the different types of interactions between signals that contribute to synergy at the biological level.

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Year:  1996        PMID: 8930538      PMCID: PMC1469489          DOI: 10.1289/ehp.961041020

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  19 in total

1.  Reduced levels of hsp90 compromise steroid receptor action in vivo.

Authors:  D Picard; B Khursheed; M J Garabedian; M G Fortin; S Lindquist; K R Yamamoto
Journal:  Nature       Date:  1990-11-08       Impact factor: 49.962

2.  High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae.

Authors:  D P McDonnell; Z Nawaz; C Densmore; N L Weigel; T A Pham; J H Clark; B W O'Malley
Journal:  J Steroid Biochem Mol Biol       Date:  1991-09       Impact factor: 4.292

3.  Synergistic activation of estrogen receptor with combinations of environmental chemicals.

Authors:  S F Arnold; D M Klotz; B M Collins; P M Vonier; L J Guillette; J A McLachlan
Journal:  Science       Date:  1996-06-07       Impact factor: 47.728

4.  The role of estrogen response elements in expression of the Xenopus laevis vitellogenin B1 gene.

Authors:  T C Chang; A M Nardulli; D Lew; D J Shapiro
Journal:  Mol Endocrinol       Date:  1992-03

5.  Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor.

Authors:  D M Ignar-Trowbridge; K G Nelson; M C Bidwell; S W Curtis; T F Washburn; J A McLachlan; K S Korach
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-15       Impact factor: 11.205

6.  A yeast estrogen screen for examining the relative exposure of cells to natural and xenoestrogens.

Authors:  S F Arnold; M K Robinson; A C Notides; L J Guillette; J A McLachlan
Journal:  Environ Health Perspect       Date:  1996-05       Impact factor: 9.031

7.  Blood levels of organochlorine residues and risk of breast cancer.

Authors:  M S Wolff; P G Toniolo; E W Lee; M Rivera; N Dubin
Journal:  J Natl Cancer Inst       Date:  1993-04-21       Impact factor: 13.506

8.  Synergism between temperature and estradiol: a common pathway in turtle sex determination?

Authors:  T Wibbels; J J Bull; D Crews
Journal:  J Exp Zool       Date:  1991-10

9.  Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes.

Authors:  K S Korach; P Sarver; K Chae; J A McLachlan; J D McKinney
Journal:  Mol Pharmacol       Date:  1988-01       Impact factor: 4.436

10.  PCBs as environmental estrogens: turtle sex determination as a biomarker of environmental contamination.

Authors:  J M Bergeron; D Crews; J A McLachlan
Journal:  Environ Health Perspect       Date:  1994-09       Impact factor: 9.031

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  4 in total

1.  Detection of hormone mimics in water using a miniturised SPR sensor.

Authors:  A M Sesay; D C Cullen
Journal:  Environ Monit Assess       Date:  2001-07       Impact factor: 2.513

2.  Synergy, antagonism, and scientific process.

Authors:  G E Hook; G W Lucier
Journal:  Environ Health Perspect       Date:  1997-08       Impact factor: 9.031

Review 3.  Hormones and health.

Authors:  M W Eubanks
Journal:  Environ Health Perspect       Date:  1997-05       Impact factor: 9.031

Review 4.  Current approaches toward chemical mixture studies at the National Institute of Environmental Health Sciences and the U.S. National Toxicology Program.

Authors:  J R Bucher; G Lucier
Journal:  Environ Health Perspect       Date:  1998-12       Impact factor: 9.031

  4 in total

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