Literature DB >> 8930382

Spatial working memory is preserved in rats treated with anabolic-androgenic steroids.

S T Smith1, R W Stackman, A S Clark.   

Abstract

The effects of anabolic-androgenic steroid (AAS) compounds on spatial working memory were evaluated in male rats. Thirty days of administration of a high dose of three individual AAS compounds (17 alpha-methyltestosterone, methandrostenolone, or testosterone cypionate) had no effects on spatial memory or motivation as tested on a delayed non-match-to-sample radial arm maze task. Administration of these AAS compounds at doses within the human abuse range does not impair spatial working memory in rats.

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Year:  1996        PMID: 8930382     DOI: 10.1016/0006-8993(96)00932-8

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  2 in total

1.  Castration in rats impairs performance during acquisition of a working memory task and exacerbates deficits in working memory produced by scopolamine and mecamylamine.

Authors:  Jill M Daniel; Peter J Winsauer; Joseph M Moerschbaecher
Journal:  Psychopharmacology (Berl)       Date:  2003-07-25       Impact factor: 4.530

2.  Testosterone impairs the acquisition of an operant delayed alternation task in male rats.

Authors:  Steven L Neese; Susan L Schantz
Journal:  Horm Behav       Date:  2011-10-25       Impact factor: 3.587

  2 in total

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