Literature DB >> 8926684

[HIT-GBM: multicenter study of treatment of children with malignant glioma].

J E Wolff1, J Boos, J Kühl.   

Abstract

The German society for paediatric oncology and hematology starts a clinical study for the treatment of children with glioblastoma, multifocal astrocytoma grade 3, brain stem grade 3 astrocytoma and typical diffuse ponsglioma. Conventional fractionated radiotherapy (54 Gy) will follow surgery. Simultaneously an additional experimental treatment will be given. The experimental treatment study will change every second year and starts with oral trofosfamide 100 mg/m2/d and VP16 25 mg/m2/d.

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Year:  1996        PMID: 8926684     DOI: 10.1055/s-2008-1046473

Source DB:  PubMed          Journal:  Klin Padiatr        ISSN: 0300-8630            Impact factor:   1.349


  6 in total

1.  Treatment options in childhood pontine gliomas.

Authors:  Sabine Wagner; Monika Warmuth-Metz; Angela Emser; Astrid-K Gnekow; Ronald Sträter; Stefan Rutkowski; Norbert Jorch; Hans-J Schmid; Frank Berthold; Norbert Graf; Rolf-D Kortmann; Thorsten Pietsch; Norbert Sörensen; Ove Peters; Johannes E A Wolff
Journal:  J Neurooncol       Date:  2006-04-06       Impact factor: 4.130

2.  High dose methotrexate for pediatric high grade glioma: results of the HIT-GBM-D pilot study.

Authors:  Johannes E Wolff; Rolf-Dieter Kortmann; Birte Wolff; Torsten Pietsch; Ove Peters; Hans-Joerg Schmid; Stefan Rutkowski; Monika Warmuth-Metz; Christoph Kramm
Journal:  J Neurooncol       Date:  2010-08-08       Impact factor: 4.130

3.  Subpopulations of malignant gliomas in pediatric patients: analysis of the HIT-GBM database.

Authors:  Johannes E A Wolff; Carl Friedrich Classen; Sabine Wagner; Rolf-Dieter Kortmann; Shana L Palla; Torsten Pietsch; Joachim Kühl; Astrid Gnekow; Christof M Kramm
Journal:  J Neurooncol       Date:  2008-01-22       Impact factor: 4.130

4.  Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma.

Authors:  Johannes E A Wolff; Christof Kramm; Rolf-Dieter Kortmann; Torsten Pietsch; Stefan Rutkowski; Norbert Jorch; Astrid Gnekow; Pablo Hernáiz Driever
Journal:  J Neurooncol       Date:  2008-08-05       Impact factor: 4.130

5.  Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas.

Authors:  Halldora K Thorarinsdottir; Mariarita Santi; Robert McCarter; Elisabeth J Rushing; Robert Cornelison; Alessandra Jales; Tobey J MacDonald
Journal:  Clin Cancer Res       Date:  2008-06-01       Impact factor: 12.531

6.  Treatment of paediatric pontine glioma with oral trophosphamide and etoposide.

Authors:  J E A Wolff; S Westphal; G Mölenkamp; A Gnekow; M Warmuth-Metz; D Rating; J Kuehl
Journal:  Br J Cancer       Date:  2002-10-21       Impact factor: 7.640

  6 in total

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