Literature DB >> 8924353

The emerging role of MIF in septic shock and infection.

J Bernhagen1, T Calandra, R Bucala.   

Abstract

The protein mediator described originally as macrophage migration inhibitory factor (MIF) has been "re-discovered" recently to be both a novel pituitary hormone and a pro-inflammatory, macrophage-derived cytokine. Emerging studies indicate that MIF plays a pivotal role not only in endotoxic shock but also in the host response to a variety of acute and chronic infections.

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Year:  1994        PMID: 8924353     DOI: 10.1007/bf01878495

Source DB:  PubMed          Journal:  Biotherapy        ISSN: 0921-299X


  14 in total

1.  Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia.

Authors:  N Honma; H Koseki; T Akasaka; T Nakayama; M Taniguchi; I Serizawa; H Akahori; M Osawa; T Mikayama
Journal:  Immunology       Date:  2000-05       Impact factor: 7.397

2.  MIF and D-DT are potential disease severity modifiers in male MS subjects.

Authors:  Gil Benedek; Roberto Meza-Romero; Kelley Jordan; Ying Zhang; Ha Nguyen; Gail Kent; Jia Li; Edwin Siu; Jenny Frazer; Marta Piecychna; Xin Du; Antoine Sreih; Lin Leng; Jack Wiedrick; Stacy J Caillier; Halina Offner; Jorge R Oksenberg; Vijayshree Yadav; Dennis Bourdette; Richard Bucala; Arthur A Vandenbark
Journal:  Proc Natl Acad Sci U S A       Date:  2017-09-18       Impact factor: 11.205

3.  Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.

Authors:  Michael Thiele; Randolf J Kerschbaumer; Frederick W K Tam; Dirk Völkel; Patrice Douillard; Alexander Schinagl; Harald Kühnel; Jennifer Smith; John P McDaid; Gurjeet Bhangal; Mei-Ching Yu; Charles D Pusey; H Terence Cook; Josef Kovarik; Erica Magelky; Atul Bhan; Manfred Rieger; Geert C Mudde; Hartmut Ehrlich; Bernd Jilma; Herbert Tilg; Alexander Moschen; Cox Terhorst; Friedrich Scheiflinger
Journal:  J Immunol       Date:  2015-07-24       Impact factor: 5.422

4.  Homotrimeric macrophage migration inhibitory factor (MIF) drives inflammatory responses in the corneal epithelium by promoting caveolin-rich platform assembly in response to infection.

Authors:  Thomas Reidy; Alexander Rittenberg; Markryan Dwyer; Samantha D'Ortona; Gerald Pier; Mihaela Gadjeva
Journal:  J Biol Chem       Date:  2013-01-31       Impact factor: 5.157

Review 5.  Orthologs of macrophage migration inhibitory factor from parasitic nematodes.

Authors:  Jon J Vermeire; Yoonsang Cho; Elias Lolis; Richard Bucala; Michael Cappello
Journal:  Trends Parasitol       Date:  2008-07-04

6.  Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii.

Authors:  Marcos Flores; Rafael Saavedra; Rocio Bautista; Rubi Viedma; Eda P Tenorio; Lin Leng; Yuriko Sánchez; Imelda Juárez; Anjali A Satoskar; Asha S Shenoy; Luis I Terrazas; Richard Bucala; Joseph Barbi; Abhay R Satoskar; Miriam Rodriguez-Sosa
Journal:  FASEB J       Date:  2008-07-07       Impact factor: 5.191

7.  CD74 deficiency ameliorates Pseudomonas aeruginosa-induced ocular infection.

Authors:  Tanweer Zaidi; Thomas Reidy; Samantha D'Ortona; Raina Fichorova; Gerald Pier; Mihaela Gadjeva
Journal:  Sci Rep       Date:  2011-08-08       Impact factor: 4.379

Review 8.  Macrophage migration inhibitory factor (MIF): a key player in protozoan infections.

Authors:  Juan de Dios Rosado; Miriam Rodriguez-Sosa
Journal:  Int J Biol Sci       Date:  2011-10-25       Impact factor: 6.580

9.  Macrophage migration inhibitory factor induces vascular leakage via autophagy.

Authors:  Hong-Ru Chen; Yung-Chun Chuang; Chiao-Hsuan Chao; Trai-Ming Yeh
Journal:  Biol Open       Date:  2015-01-23       Impact factor: 2.422

10.  Macrophage migration inhibitory factor has a permissive role in concanavalin A-induced cell death of human hepatoma cells through autophagy.

Authors:  Y-C Lai; Y-C Chuang; C-P Chang; T-M Yeh
Journal:  Cell Death Dis       Date:  2015-12-03       Impact factor: 8.469

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