Literature DB >> 892381

Clindamycin-associated colitis in hamsters: protection with vancomycin.

J G Bartlett, A B Onderdonk, R L Cisneros.   

Abstract

Clindamycin and lincomycin produced a lethal enterocolitis in 65 of 67 Syrian hamsters. The administration of oral or parenteral vancomycin to recipients of clindamycin or lincomycin was uniformly protective in 49 patients. These results suggest that certain bacteria play a role in the pathogenesis of enterocolitis in this model.

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Year:  1977        PMID: 892381

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  17 in total

1.  Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291.

Authors:  Jenessa A Winston; Rajani Thanissery; Stephanie A Montgomery; Casey M Theriot
Journal:  J Vis Exp       Date:  2016-12-10       Impact factor: 1.355

2.  Morphology of experimental antibiotic-associated enterocolitis in the hamster: a model for human pseudomembranous colitis and antibiotic-associated diarrhoea.

Authors:  A B Price; H E Larson; J Crow
Journal:  Gut       Date:  1979-06       Impact factor: 23.059

Review 3.  Clostridium difficile: its disease and toxins.

Authors:  D M Lyerly; H C Krivan; T D Wilkins
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

4.  Safety of oral vancomycin in functionally anephric patients.

Authors:  C S Bryan; W L White
Journal:  Antimicrob Agents Chemother       Date:  1978-10       Impact factor: 5.191

5.  Antimicrobial agent-associated colitis and diarrhea.

Authors:  W L George
Journal:  West J Med       Date:  1980-08

6.  Antibiotic associated colitis: in search of a cause and treatment.

Authors:  N D Gallagher; S J Goulston
Journal:  Drugs       Date:  1978-11       Impact factor: 9.546

7.  Bacitracin therapy in antibiotic-associated pseudomembranous colitis.

Authors:  F J Tedesco
Journal:  Dig Dis Sci       Date:  1980-10       Impact factor: 3.199

8.  Presence of Clostridium difficile toxin in guinea pigs with penicillin-associated colitis.

Authors:  S W Rothman
Journal:  Med Microbiol Immunol       Date:  1981       Impact factor: 3.402

9.  Pseudomembranous colitis: isolation of two species of cytotoxic clostridia and successful treatment with vancomycin.

Authors:  T J Marrie; R S Faulkner; B W Badley; M R Hartlen; S A Comeau; H R Miller
Journal:  Can Med Assoc J       Date:  1978-11-04       Impact factor: 8.262

10.  Effects of the two toxins of Clostridium difficile in antibiotic-associated cecitis in hamsters.

Authors:  J M Libby; B S Jortner; T D Wilkins
Journal:  Infect Immun       Date:  1982-05       Impact factor: 3.441

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