Literature DB >> 8923808

Cytotoxic and antioxidative sesquiterpenoids from Heterotheca inuloides.

I Kubo1, S K Chaudhuri, Y Kubo, Y Sanchez, T Ogura, T Saito, H Ishikawa, H Haraguchi.   

Abstract

Four sesquiterpenoids, beta-caryophyllene, beta-caryophyllene 4,5 alpha-oxide, 7-hydroxy-3,4-dihydrocadalin, and 7-hydroxycadalin, isolated from the dried flower of Heterotheca inuloides Cass. (Asteraceae), have been found to exhibit cytotoxic activity against several solid tumor cell lines. Among them, 7-hydroxy-3,4-dihydrocadalin and 7-hydroxycadalin have also been found to inhibit autoxidative and microsomal lipid peroxidation.

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Year:  1996        PMID： 8923808     DOI： 10.1055/s-2006-957932

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  25 in total

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3.  Cloning of a sesquiterpene synthase from Lavandula x intermedia glandular trichomes.

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Journal:  Planta       Date:  2013-08-06       Impact factor: 4.116

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5.  β-Caryophyllene, a Compound Isolated from the Biblical Balm of Gilead (Commiphora gileadensis), Is a Selective Apoptosis Inducer for Tumor Cell Lines.

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6.  Antioxidant capacity of "Mexican arnica" Heterotheca inuloides Cass natural products and some derivatives: their anti-inflammatory evaluation and effect on C. elegans life span.

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7.  Mutagenic and antimutagenic effects of Heterotheca inuloides.

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8.  Acetonic and Methanolic Extracts of Heterotheca inuloides, and Quercetin, Decrease CCl(4)-Oxidative Stress in Several Rat Tissues.

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Journal:  Evid Based Complement Alternat Med       Date:  2013-01-10       Impact factor: 2.629

9.  Trans- β -Caryophyllene: An Effective Antileishmanial Compound Found in Commercial Copaiba Oil (Copaifera spp.).

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10.  Antineuropathic effect of 7-hydroxy-3,4-dihydrocadalin in streptozotocin-induced diabetic rodents.

Authors:  Héctor Isaac Rocha-González; Magali Ramírez-Aguilar; Vinicio Granados-Soto; Juan Gerardo Reyes-García; Jorge Elías Torres-López; Juan Carlos Huerta-Cruz; Andrés Navarrete
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