OBJECTIVES: The purpose of this study was to provide more information regarding the risk of lung cancer associated with asbestos, and other exposures in the Uruguayan work force. METHODS: This multisite case-referent study was part of a large project designed for evaluating the role of occupational exposures in cancer risk in Uruguay. According to the design employed, cases were a subset of the data base corresponding to a particular site (in this instance lung cancer), and they were compared with all other sites combined (referents). RESULTS: Significant increases in risk associated with workers in the construction industry were mainly observed for squamous-cell carcinoma. Asbestos, silica dust, and DDT (dichlorodiphenyltrichloroethane) exposure were also associated with increases in the risk of lung cancer. Pipefitters, bakers, and textile workers were also at increased risk of developing lung cancer. CONCLUSIONS: Workers employed in the construction industry, as well as those exposed to DDT may have an excess risk of lung cancer. These findings are particularly important in showing that developing countries like Uruguay display risk patterns of similar magnitude as those observed in developed communities.
OBJECTIVES: The purpose of this study was to provide more information regarding the risk of lung cancer associated with asbestos, and other exposures in the Uruguayan work force. METHODS: This multisite case-referent study was part of a large project designed for evaluating the role of occupational exposures in cancer risk in Uruguay. According to the design employed, cases were a subset of the data base corresponding to a particular site (in this instance lung cancer), and they were compared with all other sites combined (referents). RESULTS: Significant increases in risk associated with workers in the construction industry were mainly observed for squamous-cell carcinoma. Asbestos, silica dust, and DDT (dichlorodiphenyltrichloroethane) exposure were also associated with increases in the risk of lung cancer. Pipefitters, bakers, and textile workers were also at increased risk of developing lung cancer. CONCLUSIONS: Workers employed in the construction industry, as well as those exposed to DDT may have an excess risk of lung cancer. These findings are particularly important in showing that developing countries like Uruguay display risk patterns of similar magnitude as those observed in developed communities.
Authors: Martin Lehnert; Thomas Behrens; Justus Tulowietzki; Karlheinz Guldner; Thomas Brüning; Dirk Taeger Journal: Int Arch Occup Environ Health Date: 2019-07-25 Impact factor: 3.015
Authors: Prerna Khetan; Paolo Boffetta; Daniele Luce; Isabelle Stucker; Maria Paula Curado; Ana Menezes; Victor Wunsch-Filho; Wolfgang Ahrens; Pagona Lagiou; Diego Serraino; Lorenzo Richiardi; Kristina Kjaerheim; David Conway; Peter Thomson; Joshua Muscat; Dana Mates; Heribert Ramroth; Gwenn Menvielle; Thomas L Vaughan; Hermann Brenner; Yuan-Chin Amy Lee; Carlo La Vecchia; Mia Hashibe; Dana Hashim Journal: J Occup Environ Med Date: 2019-05 Impact factor: 2.162
Authors: Neela Guha; Franco Merletti; Nelson Kyle Steenland; Andrea Altieri; Vincent Cogliano; Kurt Straif Journal: Environ Health Perspect Date: 2009-10-22 Impact factor: 9.031
Authors: G Menvielle; D Luce; J Févotte; I Bugel; C Salomon; P Goldberg; M-A Billon-Galland; M Goldberg Journal: Occup Environ Med Date: 2003-08 Impact factor: 4.402
Authors: Thomas Behrens; Benjamin Kendzia; Tabea Treppmann; Ann Olsson; Karl-Heinz Jöckel; Per Gustavsson; Hermann Pohlabeln; Wolfgang Ahrens; Irene Brüske; Hans-Erich Wichmann; Franco Merletti; Dario Mirabelli; Lorenzo Richiardi; Lorenzo Simonato; David Zaridze; Neonila Szeszenia-Dabrowska; Peter Rudnai; Jolanta Lissowska; Eleonora Fabianova; Adonina Tardón; John Field; Rodica Stanescu Dumitru; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Jack Siemiatycki; Marie-Elise Parent; John McLaughlin; Paul Demers; Maria Teresa Landi; Neil Caporaso; Hans Kromhout; Roel Vermeulen; Susan Peters; Simone Benhamou; Isabelle Stücker; Florence Guida; Dario Consonni; Bas Bueno-de-Mesquita; Andrea 't Mannetje; Neil Pearce; Lap Ah Tse; Ignatius Tak-sun Yu; Nils Plato; Paolo Boffetta; Kurt Straif; Joachim Schüz; Beate Pesch; Thomas Brüning Journal: Occup Environ Med Date: 2013-08-02 Impact factor: 4.402