Literature DB >> 89223

[Lymphocyte membrane receptors mediating recognition of antigens (author's transl)].

H Binz.   

Abstract

The present article summarizes briefly our knowledge of antigen-specific B- and T-lymphocyte receptors. Antigen-specific receptors on mammalian B-lymphocytes are mainly monomeric IgM and IgD consisting of conventional immunoglobulin heavy and light chains. The nature of the T-lymphocyte receptors which can specifically recognize antigens is not yet fully defined but it seems that conventional light chains do not participate in the build up of this receptor. However, T-lymphocytes express two polypeptide chains which bear variable domains sharing idiotypic determinants with the corresponding B-lymphocytes. These Tau chains can bind the corresponding antigen.

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Year:  1979        PMID: 89223     DOI: 10.1007/BF01477629

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  13 in total

1.  Immunoglobulin-receptors revisited.

Authors:  E S Vitetta; J W Uhr
Journal:  Science       Date:  1975-09-19       Impact factor: 47.728

2.  Secondary cytotoxic allograft responses in vitro. II. Differentiation of memory T cells into cytotoxic T lymphocytes in the absence of cell proliferation.

Authors:  H Wagner; M Röllinghoff
Journal:  Eur J Immunol       Date:  1976-01       Impact factor: 5.532

3.  Induction of T and B cell immunity by anti-idiotypic antibody.

Authors:  K Eichmann; K Rajewsky
Journal:  Eur J Immunol       Date:  1975-10       Impact factor: 5.532

4.  [A new allotype form of rabbit serum gamma-globulins, apparently associated with antibody function and specificity].

Authors:  J OUDIN; M MICHEL
Journal:  C R Hebd Seances Acad Sci       Date:  1963-07-17

Review 5.  Editorial: Antibody diversity: is it all coded for by the germ line genes?

Authors:  H Wigzell
Journal:  Scand J Immunol       Date:  1973       Impact factor: 3.487

Review 6.  Structure and biological properties of immunoglobulins.

Authors:  S Cohen; C Milstein
Journal:  Adv Immunol       Date:  1967       Impact factor: 3.543

7.  Aliotypic antibodies.

Authors:  H Ramseier; J Lindenmann
Journal:  Transplant Rev       Date:  1972

8.  Selection of a single antibody-forming cell clone and its propagation in syngeneic mice.

Authors:  B A Askonas; A R Williamson; B E Wright
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205

9.  Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. I. Demonstration of similar or identical idiotypes on IgG molecules and T-cell receptors with specificity for the same alloantigens.

Authors:  H Binz; H Wigzell
Journal:  J Exp Med       Date:  1975-07-01       Impact factor: 14.307

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