Literature DB >> 89211

Inhibition of spontaneous transformation of rat embryo cells releasing endogenous type C virus by virus-specific antiserum.

S Rasheed, H Young, M B Gardner.   

Abstract

Noninbred Sprague-Dawley rat embryo cell clones predictably undergo transformation after 20-30 in vitro passages following spontaneous release of endogenous rat leukemia virus (RaLV). In the presence of RaLV-specific antiserum, virus production and infectivity were reduced and transformation was delayed from 6 to 25 weeks. Transformation was not associated with an increased expression of Kirsten murine sarcoma virus-related src gene RNA.

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Year:  1979        PMID： 89211     DOI： 10.1093/jnci/63.3.745

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  4 in total

1.  Molecular cloning, genomic analysis, and biological properties of rat leukemia virus and the onc sequences of Rasheed rat sarcoma virus.

Authors:  M A Gonda; H A Young; J E Elser; S Rasheed; C B Talmadge; K Nagashima; C C Li; R V Gilden
Journal:  J Virol       Date:  1982-11       Impact factor: 5.103

2.  Inhibition of rat yolk sac tumour growth in vivo by a monoclonal antibody to the retroviral molecule P15E.

Authors:  M Lindvall; H O Sjögren
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

3.  Rat sarcoma virus: further analysis of individual viral isolates and the gene product.

Authors:  H A Young; S Rasheed; R Sowder; C V Benton; L E Henderson
Journal:  J Virol       Date:  1981-04       Impact factor: 5.103

4.  Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus.

Authors:  R W Ellis; D DeFeo; J M Maryak; H A Young; T Y Shih; E H Chang; D R Lowy; E M Scolnick
Journal:  J Virol       Date:  1980-11       Impact factor: 5.103
  4 in total

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