Literature DB >> 8919279

Is there a causal connection between bile acids and colorectal cancer?

A Tocchi1, L Basso, G Costa, L Lepre, G Liotta, G Mazzoni, A Sita, S Tagliacozzo.   

Abstract

Bile acid composition was assessed in 50 patients with colorectal cancer as compared to that in a control group of 50 subjects. The two groups were age- and sex-matched. The overall bile acid values were similar in both groups, while the relative concentrations of primary and secondary bile acids were different, a significant increase in the patients with colorectal cancer being observed. This finding thus seems to confirm the existence of a link between colorectal cancer and cholelithiasis. Both conditions share common risk factors, such as alterations in cholesterol metabolism and bile acid composition.

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Year:  1996        PMID： 8919279     DOI： 10.1007/bf00311772

Source DB:  PubMed          Journal:  Surg Today        ISSN： 0941-1291            Impact factor:   2.549


  32 in total

1.  Control of deoxyribonucleic acid synthesis in normal rabbit colonic mucosa.

Authors:  D H Alpers; G W Philpott
Journal:  Gastroenterology       Date:  1975-10       Impact factor: 22.682

2.  Effects of high risk and low risk diets for colon carcinogenesis on fecal microflora and steroids in man.

Authors:  B S Reddy; J H Weisburger; E L Wynder
Journal:  J Nutr       Date:  1975-07       Impact factor: 4.798

3.  Modification of DNA by bile acids: a possible factor in the etiology of colon cancer.

Authors:  P Y Cheah; H Bernstein
Journal:  Cancer Lett       Date:  1990-03       Impact factor: 8.679

4.  Bacteria and aetiology of cancer of large bowel.

Authors:  M J Hill; B S Drasar; G Hawksworth; V Aries; J S Crowther; R E Williams
Journal:  Lancet       Date:  1971-01-16       Impact factor: 79.321

5.  Metabolic epidemiology of colon cancer: effect of dietary fiber on fecal mutagens and bile acids in healthy subjects.

Authors:  B S Reddy; C Sharma; B Simi; A Engle; K Laakso; P Puska; R Korpela
Journal:  Cancer Res       Date:  1987-01-15       Impact factor: 12.701

6.  Cholecystectomy and colonic cancer.

Authors:  D Blanco; R K Ross; A Paganini-Hill; B E Henderson
Journal:  Dis Colon Rectum       Date:  1984-05       Impact factor: 4.585

7.  Gallstones and risk of colonic cancer: a matched case-control study.

Authors:  M Gafà; L Sarli; G Sansebastiano; M Lupi; E Longinotti; P P Rigamonti; A Peracchia
Journal:  Int Surg       Date:  1987 Jan-Mar

8.  Faecal unconjugated bile acids in patients with colorectal cancer or polyps.

Authors:  C H Imray; S Radley; A Davis; G Barker; C W Hendrickse; I A Donovan; A M Lawson; P R Baker; J P Neoptolemos
Journal:  Gut       Date:  1992-09       Impact factor: 23.059

9.  Bile acid receptors in colorectal cancer.

Authors:  J Summerton; M Flynn; T Cooke; I Taylor
Journal:  Br J Surg       Date:  1983-09       Impact factor: 6.939

10.  Fecal free and conjugated bile acids and neutral sterols in vegetarians, omnivores, and patients with colorectal cancer.

Authors:  J T Korpela; H Adlercreutz; M J Turunen
Journal:  Scand J Gastroenterol       Date:  1988-04       Impact factor: 2.423
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  2 in total

1.  Identification of functional modules that correlate with phenotypic difference: the influence of network topology.

Authors:  Jui-Hung Hung; Troy W Whitfield; Tun-Hsiang Yang; Zhenjun Hu; Zhiping Weng; Charles DeLisi
Journal:  Genome Biol       Date:  2010-02-26       Impact factor: 13.583

2.  Bile acid analysis in biliary tract cancer.

Authors:  Jeong Youp Park; Byung Kyu Park; Jun Sang Ko; Seungmin Bang; Si Young Song; Jae Bock Chung
Journal:  Yonsei Med J       Date:  2006-12-31       Impact factor: 2.759
  2 in total

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