Literature DB >> 891873

Reduction of bovine pulmonary hypertension by normoxia, verapamil and hexoprenaline.

I F McMurtry, J T Reeves, D H Will, R F Grover.   

Abstract

In calves with hypoxic pulmonary hypertension, resistance was reduced by 40 +/- 3% with normoxia, 19 +/- 4% with verapamil, and 60 +/- 1% with hexoprenaline. It is possible that the increased resistance during normoxia is due to partly to vasoconstriction rather than solely to vascular thickening, and that the vasoconstriction is due to an abnormality in calcium metabolism by the hypertensive vasculature.

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Year:  1977        PMID： 891873     DOI： 10.1007/bf01922322

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  22 in total

1.  PULMONARY VASCULAR PATHOLOGY OF BOVINE HIGH MOUNTAIN DISEASE.

Authors:  A F ALEXANDER; R JENSEN
Journal:  Am J Vet Res       Date:  1963-11       Impact factor: 1.156

2.  High altitude-induced pulmonary hypertension in normal cattle.

Authors:  D H WILL; A F ALEXANDER; J T REEVES; R F GROVER
Journal:  Circ Res       Date:  1962-02       Impact factor: 17.367

3.  Cyclic AMP and calcium ions in mechanical and metabolic responses of smooth muscles; influence of some hormones and drugs.

Authors:  R G Andersson
Journal:  Acta Physiol Scand Suppl       Date:  1972

4.  The significance of cyclic 3'5-AMP for the Euler-Liljestrand mechanism.

Authors:  V Sill; E Kaukel; N Völkel; S Siemssen
Journal:  Pneumonologie       Date:  1974

5.  The effect of verapamil on the response to noradrenaline or to potassium-depolarization in isolated vascular strips.

Authors:  I Bilek; R Laven; U Peiper; K Regnat
Journal:  Microvasc Res       Date:  1974-03       Impact factor: 3.514

6.  Bradycardia, increased cardiac output, and reversal of pulmonary hypertension in altitude natives living at sea level.

Authors:  F Sime; D Peñaloza; L Ruiz
Journal:  Br Heart J       Date:  1971-09

7.  Hypertensive pulmonary vascular disease in states of chronic hypoxia.

Authors:  P S Hasleton; D Heath; D B Brewer
Journal:  J Pathol Bacteriol       Date:  1968-04

8.  Attenuation of hypoxic pulmonary vasoconstriction by verapamil in intact dogs.

Authors:  A Tucker; I F McMurtry; R F Grover; J T Reeves
Journal:  Proc Soc Exp Biol Med       Date:  1976-03

9.  Cardiovascular actions of iproveratril.

Authors:  G Ross; C R Jorgensen
Journal:  J Pharmacol Exp Ther       Date:  1967-12       Impact factor: 4.030

10.  Effects of hypoxia on the distribution of calcium in arterial smooth muscle cells of rats and swine.

Authors:  D W Haack; J H Abel; R S Jaenke
Journal:  Cell Tissue Res       Date:  1975       Impact factor: 5.249
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  4 in total

Review 1.  Pulmonary hypertension.

Authors:  J R Michael; W R Summer
Journal:  Lung       Date:  1985       Impact factor: 2.584

2.  Separate and combined use of verapamil, aspirin and captopril in experimental chronic pulmonary hypertension.

Authors:  D Kentera; D Susić; M Zdravković
Journal:  Basic Res Cardiol       Date:  1984 May-Jun       Impact factor: 17.165

3.  Effects of verapamil on pulmonary haemodynamics during hypoxaemia, at rest, and during exercise in patients with chronic obstructive pulmonary disease.

Authors:  S E Brown; G S Linden; R R King; G P Blair; D W Stansbury; R W Light
Journal:  Thorax       Date:  1983-11       Impact factor: 9.139

4.  Resolution of pulmonary hypertension and other features induced by chronic hypoxia in rats during complete and intermittent normoxia.

Authors:  J Herget; A J Suggett; E Leach; G R Barer
Journal:  Thorax       Date:  1978-08       Impact factor: 9.139
  4 in total

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