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Literature DB >> 891850

Reductive dechlorination of chlorobiphenylols by rats.

Abstract

Dechlorinated products were isolated from the urine of rats that were administered chlorobiphenylols, the primary hydroxylated metabolites of PCB in mammals. The mechanism of chlorine loss from chlorobiphenylols is different from the mechanism of dechlorination via arene oxides whereby concomitant hydroxylation is always observed.

Entities: Chemical Gene Species

Mesh：

Substances：
Biphenyl Compounds

Year: 1977 PMID： 891850 DOI： 10.1007/bf01922284

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

7 in total

1. Metabolic dechlorination of toxaphene in rats.

Authors: T Ohsawa; J R Knox; S Khalifa; J E Casida
Journal: J Agric Food Chem Date: 1975 Jan-Feb Impact factor: 5.279

2. Metabolism and effects of hexachlorobenzene on hepatic microsomal enzymes in the rat.

Authors: H M Mehendale; M Fields; H B Mathews
Journal: J Agric Food Chem Date: 1975 Mar-Apr Impact factor: 5.279

3. Metabolism of 4,4'-dihalogenobiphenyls.

Authors: S Safe; D Jones; O Hutzinger
Journal: J Chem Soc Perkin 1 Date: 1976

4. Mass spectrometry of the methyl esthers of isomeric hydroxychlorobiphenyls--potential metabolites of chlorobiphenyls.

Authors: B Jansson; G Sundström
Journal: Biomed Mass Spectrom Date: 1974-12

5. Photochemistry of bioactive compounds. Photochemical processes of polychlorinated biphenyls.

Authors: L O Ruzo; M J Zabik; R D Schuetz
Journal: J Am Chem Soc Date: 1974-06-12 Impact factor: 15.419

6. Preparation, gas chromatographic behavior, and spectroscopic properties of hydroxylated chlorobiphenyls.

Authors: O Hutzinger; S Safe; V Zitko
Journal: J Assoc Off Anal Chem Date: 1974-09

7. The metabolism of hexachlorobenzene (HCB) in rats.

Authors: R Engst; R M Macholz; M Kujawa
Journal: Bull Environ Contam Toxicol Date: 1976-08 Impact factor: 2.151

7 in total

4 in total

Reductive dechlorination of chlorobiphenylols by rats.

1. Metabolic dechlorination of toxaphene in rats.

2. Metabolism and effects of hexachlorobenzene on hepatic microsomal enzymes in the rat.

3. Metabolism of 4,4'-dihalogenobiphenyls.

4. Mass spectrometry of the methyl esthers of isomeric hydroxychlorobiphenyls--potential metabolites of chlorobiphenyls.

5. Photochemistry of bioactive compounds. Photochemical processes of polychlorinated biphenyls.

6. Preparation, gas chromatographic behavior, and spectroscopic properties of hydroxylated chlorobiphenyls.

7. The metabolism of hexachlorobenzene (HCB) in rats.

1. Hydroxylated metabolites of 4-monochlorobiphenyl and its metabolic pathway in whole poplar plants.

2. Metabolism of 3-Chlorobiphenyl (PCB 2) in a Human-Relevant Cell Line: Evidence of Dechlorinated Metabolites.

3. PCB Sulfates in Serum from Mothers and Children in Urban and Rural U.S. Communities.

4. Excretion, distribution and metabolism of 1,2,4-trichlorobenzene in rats.