Literature DB >> 891841

Dissociation of obesity, hypercholesterolemia and diabetes from atherosclerosis in ob/ob mice.

T T Yen, J A Allan, D V Pearson, M R Schinitsky.   

Abstract

Genetically obese, diabetic and hypercholesterolemic C57BL/6J-ob/ob mice were placed on Purina Laboratory Chow containing 2% cholesterol for up to 4 months. They developed higher plasma cholesterol levels and accumulated an increased quantity of cholesterol in the liver but failed to develop atherosclerotic lesions in the aorta as would be expected in an obese, diabetic and hypercholesterolemic human adult.

Entities:  

Mesh:

Year:  1977        PMID: 891841     DOI: 10.1007/bf01945927

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  4 in total

1.  Acetate metabolism: effects of tracer concentration.

Authors:  R J EMERSON; J T VAN BRUGGEN
Journal:  Arch Biochem Biophys       Date:  1958-10       Impact factor: 4.013

2.  Hypercholesteremia in the hereditary obese-hyperglycemic syndrome of mice.

Authors:  J MAYER; A K JONES
Journal:  Am J Physiol       Date:  1953-12

3.  A new method for the direct determination of serum cholesterol.

Authors:  A ZLATKIS; B ZAK; A J BOYLE
Journal:  J Lab Clin Med       Date:  1953-03

4.  Studies on lipogenesis in vivo: Fatty acid and cholesterol synthesis in hyperglycaemic-obese mice.

Authors:  G R Jansen; M E Zanetti; C F Hutchison
Journal:  Biochem J       Date:  1967-03       Impact factor: 3.857

  4 in total
  6 in total

1.  Are common leptin promoter polymorphisms associated with restenosis after coronary stenting?

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Review 2.  Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease.

Authors:  Seth S Martin; Atif Qasim; Muredach P Reilly
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Review 3.  Adipose tissue: a motor for the inflammation associated with obesity.

Authors:  Vidula Vachharajani; D Neil Granger
Journal:  IUBMB Life       Date:  2009-04       Impact factor: 3.885

4.  Obesity and endoplasmic reticulum (ER) stresses.

Authors:  Yamini B Tripathi; Vivek Pandey
Journal:  Front Immunol       Date:  2012-08-07       Impact factor: 7.561

Review 5.  Role of Leptin in Cardiovascular Diseases.

Authors:  Mareike S Poetsch; Anna Strano; Kaomei Guan
Journal:  Front Endocrinol (Lausanne)       Date:  2020-06-16       Impact factor: 5.555

6.  The Influence of Photoperiod on the Action of Exogenous Leptin on Gene Expression of Proinflammatory Cytokines and Their Receptors in the Thoracic Perivascular Adipose Tissue (PVAT) in Ewes.

Authors:  Agata Krawczyńska; Andrzej P Herman; Hanna Antushevich; Joanna Bochenek; Karolina Wojtulewicz; Dorota A Zięba
Journal:  Mediators Inflamm       Date:  2019-11-12       Impact factor: 4.711

  6 in total

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