Literature DB >> 891818

Changes in gentamicin pharmacokinetics after reduction of renal parenchyma.

O Schück, J Morávek, M Hatala.   

Abstract

The relationship between the elimination constant of gentamicin and the percentage of functioning nephrons in rats cannot be characterized by a simple linear relation. The results support the assumption that gentamicin elimination per residual nephron increased.

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Year:  1977        PMID: 891818     DOI: 10.1007/bf01945978

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  3 in total

1.  Drug dosage in patients with renal disease.

Authors:  L C Dettli
Journal:  Clin Pharmacol Ther       Date:  1974-07       Impact factor: 6.875

2.  Compensatory renal hypertrophy in young rats: Increase in the number of nephrons.

Authors:  J P Bonvalet; M Champion; F Wanstok; G Berjal
Journal:  Kidney Int       Date:  1972-06       Impact factor: 10.612

3.  Gentamicin pharmacokinetics in rats with reduced renal parenchyma.

Authors:  M Hatala; J Morávek; O Schück
Journal:  Int J Clin Pharmacol Biopharm       Date:  1975-01
  3 in total

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