Literature DB >> 891796

Isotope effect studies on the dehydrogenation of delta 1-tetrahydrocannabinol in the rat.

N K McCallum, A Gugelmann, C A Brenninkmeijer, R Mechoulam.   

Abstract

Isotope effect studies on the metabolic dehydrogenation of delta 1-tetrahydrocannabinol in rats are described and it is shown that this process is confined to a very short period following i.v. administration. The implications of this finding are discussed.

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Year:  1977        PMID： 891796     DOI： 10.1007/bf01945939

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  The effect of cannabinol delta1-tetrahydro-cannabinol clearance from the blood.

Authors:  N K McCallum
Journal:  Experientia       Date:  1975-08-15

2.  Cannabinol: a rapidly formed metabolite of delta-1- and delta-6-tetrahydrocannabinol.

Authors:  N D McCallum; B Yagen; S Levy; R Mechoulam
Journal:  Experientia       Date:  1975-05-15

3.  The durations of action of thiopental and pentobarbital.

Authors:  A GOLDSTEIN; L ARONOW
Journal:  J Pharmacol Exp Ther       Date:  1960-01       Impact factor: 4.030

4.  Lipid solubility and drug penetration of the blood brain barrier.

Authors:  W H Oldendorf
Journal:  Proc Soc Exp Biol Med       Date:  1974-12

5.  Modification of delta9-THC-actions by cannabinol and cannabidiol in the rat.

Authors:  M Fernandes; A Schabarek; H Coper; R Hill
Journal:  Psychopharmacologia       Date:  1974

6.  Physiochemical properties, solubility, and protein binding of delta9-tetrahydrocannabinol.

Authors:  E R Garrett; C A Hunt
Journal:  J Pharm Sci       Date:  1974-07       Impact factor: 3.534

7.  Chemical basis of hashish activity.

Authors:  R Mechoulam; A Shani; H Edery; Y Grunfeld
Journal:  Science       Date:  1970-08-07       Impact factor: 47.728

8.  Delta-9-tetrahydrocannabinol: metabolism and disposition in long-term marihuana smokers.

Authors:  L Lemberger; N R Tamarkin; J Axelrod; I J Kopin
Journal:  Science       Date:  1971-07-02       Impact factor: 47.728
  8 in total

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