Literature DB >> 891613

Effects of amphetamine on brain biogenic amines in isolated and aggregated rats.

F Lokiec, C Jacquot, J R Rapin, Y Cohen.   

Abstract

d- and 1-amphetamine were injected (15 mg/kg i.p.) into isolated or aggregated rats. Both d- and 1-forms decreased the noradrenaline levels of brain areas in isolated and in aggregated rats. d-Amphetamine decreased 5-hydroxytryptamine (5-HT) and 5-hydroxyindolacetic acid (5-hiaa) levels in aggregated rats only. 1-Amphetamine induced no change in 5-HT and 5-HIAA levels. The greater sensitivity of aggregated rats to d-amphetamine can be ascribed to a change in 5-HT metabolism rather than to a modification of noradrenaline levels.

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Year:  1977        PMID： 891613     DOI： 10.1016/0014-2999(77)90314-4

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  4 in total

1.  A comparison of the kinetics of d- and l-amphetamine in the brain of isolated and aggregated rats.

Authors:  F Lokiec; J R Rapin; C Jacquot; Y Cohen
Journal:  Psychopharmacology (Berl)       Date:  1978-06-15       Impact factor: 4.530

2.  The ontogeny of aggregation-enhanced toxicity.

Authors:  G C Wagner; J B Lucot; C R Schuster; L S Seiden
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

3.  Cageing density and dopamine striatal elimination after amphetamine in the rat.

Authors:  F Lokiec; Y Cohen; C Jacquot
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

4.  MDMA: a social drug in a social context.

Authors:  Matthew G Kirkpatrick; Harriet de Wit
Journal:  Psychopharmacology (Berl)       Date:  2014-10-05       Impact factor: 4.530
  4 in total

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