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Literature DB >> 891592

Differences in the binding of drugs to plasma proteins from newborn and adult man. I.

Abstract

The binding of various drugs to plasma proteins from adult and cord plasma was determined by equilibrium dialysis. For almost all the drugs binding to cord plasma was lower than to plasma from adults. No evidence was found that the difference in binding was due to the different protein concentration in cord and adult plasma or to an influence of substances in ultrafiltrates of the plasmas.

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Year: 1977 PMID： 891592 DOI： 10.1007/bf00562940

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

25 in total

1. The importance of dissociaton constant and lipid-solubility in influencing the passage of drugs into the cerebrospinal fluid.

Authors: B B BRODIE; H KURZ; L S SCHANKER
Journal: J Pharmacol Exp Ther Date: 1960-09 Impact factor: 4.030

2. [P-aminosalicyclic acid and isonicotinic acid hydrazide in parenchymatous organs after separate and combined administration].

Authors: D AURES; E WERLE
Journal: Arzneimittelforschung Date: 1957-04

3. Estimation of morphine in biological materials.

Authors: L A WOODS; J COCHIN; E G FORNEFELD; M H SEEVERS
Journal: J Pharmacol Exp Ther Date: 1954-05 Impact factor: 4.030

4. The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-amino-phenol, free and total conjugated, in biological fluids and tissues.

Authors: B B BRODIE; J AXELROD
Journal: J Pharmacol Exp Ther Date: 1948-09 Impact factor: 4.030

5. The fate of acetophenetidin in man and methods for the estimation of acetophenetidin and its metabolites in biological material.

Authors: B B BRODIE; J AXELROD
Journal: J Pharmacol Exp Ther Date: 1949-09 Impact factor: 4.030

6. Biochemical studies on chloramphenicol; colorimetric methods for the determination of chloramphenicol and related nitro compounds.

Authors: A J GLAZKO; L M WOLF; W A DILL
Journal: Arch Biochem Date: 1949-10

7. The fate of thiopental in man and a method for its estimation in biological material.

Authors: B B BRODIE; L C MARK
Journal: J Pharmacol Exp Ther Date: 1950-01 Impact factor: 4.030

8. A comparison of the binding of drugs to adult and cord plasma.

Authors: A W Pruitt; P G Dayton
Journal: Eur J Clin Pharmacol Date: 1971-12 Impact factor: 2.953

9. Age differences in drug binding by plasma proteins: studies on human foetuses, neonates and adults.

Authors: M Ehrnebo; S Agurell; B Jalling; L O Boréus
Journal: Eur J Clin Pharmacol Date: 1971-09 Impact factor: 2.953

10. Evaluation of methods to determine protein-binding of drugs. Equilibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration.

Authors: H Kurz; H Trunk; B Weitz
Journal: Arzneimittelforschung Date: 1977-07

19 in total

Review 1. Plasma protein binding of drugs in pregnancy and in neonates.

Authors: L J Notarianni
Journal: Clin Pharmacokinet Date: 1990-01 Impact factor: 6.447

2. Differences in the binding of drugs to plasma proteins from newborn and adult man. II.

Authors: H Kurz; H Michels; H H Stickel
Journal: Eur J Clin Pharmacol Date: 1977-07-19 Impact factor: 2.953

3. [Pharmaco-kinetic aspects of protein-binding (author's transl)].

Authors: H Kurz
Journal: Klin Wochenschr Date: 1978-12-15

Review 4. Clinical pharmacology of the perinatal period and early infancy.

Authors: P L Morselli
Journal: Clin Pharmacokinet Date: 1989 Impact factor: 6.447

Review 5. Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (Part II).

Authors: J B Besunder; M D Reed; J L Blumer
Journal: Clin Pharmacokinet Date: 1988-05 Impact factor: 6.447

6. Demonstration of 2-hydroxybenzoylglycine as a drug binding inhibitor in newborn infants.

Authors: B Suh; S J Wadsworth; D M Lichtenwalner
Journal: J Clin Invest Date: 1987-10 Impact factor: 14.808

Review 7. Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics.

Authors: H Nau; W Kuhnz; H J Egger; D Rating; H Helge
Journal: Clin Pharmacokinet Date: 1982 Nov-Dec Impact factor: 6.447

Review 8. Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.

Authors: J H Kanto
Journal: Drugs Date: 1982-05 Impact factor: 9.546

Review 9. Clinical pharmacokinetics of chloramphenicol and chloramphenicol succinate.

Authors: P J Ambrose
Journal: Clin Pharmacokinet Date: 1984 May-Jun Impact factor: 6.447

10. Infants and young children metabolise codeine to morphine. A study after single and repeated rectal administration.

Authors: H Quiding; G L Olsson; L O Boreus; U Bondesson
Journal: Br J Clin Pharmacol Date: 1992-01 Impact factor: 4.335