PURPOSE: The subject of this study was to define age-related and gender-dependent changes in MR features of the lacrimal gland. MATERIAL AND METHODS: MR images were retrospectively analyzed in 104 normal subjects aged 2-79 years to measure thickness and area of the lacrimal gland, its MR signal intensity ratio, and SD of the MR signal intensity profile. RESULTS: Thickness and area of the lacrimal gland decreased with age in women (p < 0.001), but not in men. Furthermore, MR signal intensity ratio of the lacrimal gland showed an age-related increase in women (p < 0.001), but not in men. On the other hand, SD of the MR signal intensity increased with age in both women and men (p < 0.001). CONCLUSION: These findings demonstrate that gender has a significant influence on lacrimal gland structure during development and aging.
PURPOSE: The subject of this study was to define age-related and gender-dependent changes in MR features of the lacrimal gland. MATERIAL AND METHODS: MR images were retrospectively analyzed in 104 normal subjects aged 2-79 years to measure thickness and area of the lacrimal gland, its MR signal intensity ratio, and SD of the MR signal intensity profile. RESULTS: Thickness and area of the lacrimal gland decreased with age in women (p < 0.001), but not in men. Furthermore, MR signal intensity ratio of the lacrimal gland showed an age-related increase in women (p < 0.001), but not in men. On the other hand, SD of the MR signal intensity increased with age in both women and men (p < 0.001). CONCLUSION: These findings demonstrate that gender has a significant influence on lacrimal gland structure during development and aging.
Authors: José David Ríos; Yoshitaka Horikawa; Li-Li Chen; Claire L Kublin; Robin R Hodges; Darlene A Dartt; Driss Zoukhri Journal: Exp Eye Res Date: 2005-04 Impact factor: 3.467
Authors: Y Seo; Y W Ji; S M Lee; J Shim; H Noh; A Yeo; C Park; M S Park; E J Chang; H K Lee Journal: Cell Death Dis Date: 2014-06-26 Impact factor: 8.469