| Literature DB >> 8914574 |
B Mackenzie1, Y J Fei, V Ganapathy, F H Leibach.
Abstract
The human intestinal H+/oligopeptide cotransporter hPEPT1, expressed in Xenopus oocytes, transported neutral, anionic and cationic dipeptides with identical electrogenic properties and maximal evoked currents. Currents were activated by 1 H+ regardless of the net charge on the driven substrate, and were independent of Na+o, K+i and Clo-, calling into question the familiar concept of the origin of the transporter-mediated current.Entities:
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Year: 1996 PMID: 8914574 DOI: 10.1016/s0005-2736(96)00170-8
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002