Literature DB >> 8912273

Age-related changes in baroreflex control of heart rate and sympathetic nerve activity in healthy humans.

T Matsukawa1, Y Sugiyama, T Mano.   

Abstract

To determine how the baroreflex control of sympathetic nerve activity is affected by aging, muscle sympathetic nerve activity (MSNA) from the tibial nerve was monitored using microneurography, and heart rate and blood pressure were recorded during the pressor or depressor responses to intravenous injections of phenylephrine or nitroglycerin in 39 healthy humans, aged 16 to 56 years. Although the baroreflex slope for heart rate showed attenuation with aging, the baroreflex slope for MSNA was not affected by aging. These data suggest preservation of the baroreflex control of sympathetic nerve activity despite attenuation of the baroreflex control of parasympathetic nerve activity by aging in humans.

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Year:  1996        PMID: 8912273     DOI: 10.1016/0165-1838(96)00057-4

Source DB:  PubMed          Journal:  J Auton Nerv Syst        ISSN: 0165-1838


  21 in total

1.  Two sites for modulation of human sympathetic activity by arterial baroreceptors?

Authors:  P Kienbaum; T Karlssonn; Y B Sverrisdottir; M Elam; B G Wallin
Journal:  J Physiol       Date:  2001-03-15       Impact factor: 5.182

2.  Effect of aging on carotid baroreflex control of blood pressure and leg vascular conductance in women.

Authors:  Daniel P Credeur; Seth W Holwerda; Leryn J Boyle; Lauro C Vianna; Areum K Jensen; Paul J Fadel
Journal:  Am J Physiol Heart Circ Physiol       Date:  2014-03-28       Impact factor: 4.733

3.  Age- and fitness-related alterations in vascular sympathetic control.

Authors:  Péter Studinger; Richard Goldstein; J Andrew Taylor
Journal:  J Physiol       Date:  2009-03-09       Impact factor: 5.182

4.  Influence of ageing on carotid baroreflex peak response latency in humans.

Authors:  James P Fisher; Areum Kim; Colin N Young; Shigehiko Ogoh; Peter B Raven; Niels H Secher; Paul J Fadel
Journal:  J Physiol       Date:  2009-10-05       Impact factor: 5.182

5.  The effect of aging on phenylephrine response in normal subjects.

Authors:  Kenneth M Madden; Wayne C Levy; Arnold Jacobson; John R Stratton
Journal:  J Am Aging Assoc       Date:  2003-01

Review 6.  Beneficial effects of physical activity on baroreflex control in the elderly.

Authors:  Maria Teresa La Rovere; Gian Domenico Pinna
Journal:  Ann Noninvasive Electrocardiol       Date:  2014-05-21       Impact factor: 1.468

7.  Alterations in dietary sodium intake affect cardiovagal baroreflex sensitivity.

Authors:  Matthew C Babcock; Michael S Brian; Joseph C Watso; David G Edwards; Sean D Stocker; Megan M Wenner; William B Farquhar
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2018-06-27       Impact factor: 3.619

8.  Usefulness of tilt-induced heart rate changes in the differential diagnosis of vasovagal syncope and chronic autonomic failure.

Authors:  Maria J Téllez; Lucy J Norcliffe-Kaufmann; Svetlana Lenina; Andrei Voustianiouk; Horacio Kaufmann
Journal:  Clin Auton Res       Date:  2009-12       Impact factor: 4.435

Review 9.  New insights into the effects of age and sex on arterial baroreflex function at rest and during dynamic exercise in humans.

Authors:  James P Fisher; Areum Kim; Doreen Hartwich; Paul J Fadel
Journal:  Auton Neurosci       Date:  2012-11-11       Impact factor: 3.145

10.  Baroreflex sensitivity analysis: spontaneous methodology vs. Valsalva's maneuver.

Authors:  Huan Yang; Jason R Carter
Journal:  Clin Auton Res       Date:  2013-05-16       Impact factor: 4.435

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