Literature DB >> 8911774

Age-related differences in the chronic and acute response to cocaine in the rat.

B P Bowman1, C M Kuhn.   

Abstract

Behavioral sensitization is known to occur in adult animals after the chronic intermittent administration of cocaine. Dopaminergic pathways in the brain, such as the nigrostriatal and mesoaccumbens projections play a vital role in this phenomenon. These pathways are rudimentary in the 1st week of life, indicating that the developing animal may be unable to respond to cocaine in the same manner as an adult. In the present study, we report that the acute response to cocaine is remarkably similar between week-old and adult rats. Pups do not, however, show locomotor sensitization to acute cocaine after chronic cocaine-administration as adults.

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Year:  1996        PMID： 8911774     DOI： 10.1002/(SICI)1098-2302(199611)29:7<597::AID-DEV4>3.0.CO;2-P

Source DB:  PubMed          Journal:  Dev Psychobiol        ISSN： 0012-1630            Impact factor:   3.038


  15 in total

1.  Plasma cocaine levels, metabolites, and locomotor activity after subcutaneous cocaine injection are stable across the postpartum period in rats.

Authors:  Michael P Wansaw; Shen-Nan Lin; Joan I Morrell
Journal:  Pharmacol Biochem Behav       Date:  2005-08-22       Impact factor: 3.533

2.  Acute and chronic methylphenidate dose-response assessment on three adolescent male rat strains.

Authors:  Pamela B Yang; Alan C Swann; Nachum Dafny
Journal:  Brain Res Bull       Date:  2006-10-19       Impact factor: 4.077

Review 3.  Differential effects of psychoactive drugs in adolescents and adults.

Authors:  Sari Izenwasser
Journal:  Crit Rev Neurobiol       Date:  2005

4.  Estrous cycle and sex affect cocaine-induced behavioural changes in CD1 mice.

Authors:  Mariangela Martini; Ana Xavier Pinto; Olga Valverde
Journal:  Psychopharmacology (Berl)       Date:  2014-01-23       Impact factor: 4.530

Review 5.  Estradiol: a key biological substrate mediating the response to cocaine in female rats.

Authors:  Annabell C Segarra; José L Agosto-Rivera; Marcelo Febo; Natasha Lugo-Escobar; Raissa Menéndez-Delmestre; Anabel Puig-Ramos; Yvonne M Torres-Diaz
Journal:  Horm Behav       Date:  2009-12-21       Impact factor: 3.587

6.  Sex differences in novelty- and psychostimulant-induced behaviors of C57BL/6 mice.

Authors:  Amanda E D Van Swearingen; Q David Walker; Cynthia M Kuhn
Journal:  Psychopharmacology (Berl)       Date:  2012-09-14       Impact factor: 4.530

7.  Sex chromosome complement influences vulnerability to cocaine in mice.

Authors:  Mariangela Martini; Joshua W Irvin; Christina G Lee; Wendy J Lynch; Emilie F Rissman
Journal:  Horm Behav       Date:  2020-08-06       Impact factor: 3.587

8.  Acute and chronic psychostimulant treatment modulates the diurnal rhythm activity pattern of WKY female adolescent rats.

Authors:  Cathleen G Jones; Pamela B Yang; Victor T Wilcox; Keith D Burau; Nachum Dafny
Journal:  J Neural Transm (Vienna)       Date:  2014-01-31       Impact factor: 3.575

9.  Adult female rats' altered diurnal locomotor activity pattern following chronic methylphenidate treatment.

Authors:  T N Trinh; S R Kohllepel; P B Yang; K D Burau; N Dafny
Journal:  J Neural Transm (Vienna)       Date:  2013-07-27       Impact factor: 3.575

10.  Sensitivity to cocaine conditioned reward depends on sex and age.

Authors:  Elena Zakharova; Dean Wade; Sari Izenwasser
Journal:  Pharmacol Biochem Behav       Date:  2008-11-12       Impact factor: 3.533
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