| Literature DB >> 8910882 |
Abstract
The author proposes that all major risk factors, including elevated serum low-density lipoprotein, cause atherosclerosis by increasing viscosity, creating larger areas of decreased blood flow, thereby perpetuating the interaction of atherogenic elements with the endothelium. Low-density lipoprotein causes increased viscosity by fostering erythrocyte aggregation. High-density lipoprotein protects against atherosclerosis by antagonizing erythrocyte aggregation, thereby decreasing viscosity. Implications of this theory are discussed.Entities:
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Year: 1996 PMID： 8910882 DOI： 10.1016/s0306-9877(96)90073-0
Source DB: PubMed Journal: Med Hypotheses ISSN： 0306-9877 Impact factor: 1.538