Literature DB >> 8909807

Regulation of the actin cytoskeleton, integrins and cell growth by the Rho family of small GTPases.

N A Hotchin1, A Hall.   

Abstract

The Rho family of small GTP binding proteins play a key part in regulating the actin cytoskeleton and cell adhesion through integrin receptors. In addition, these proteins regulate signal transduction pathways essential for normal cell growth. Many of the molecules that regulate Rho have oncogenic activity, suggesting that members of the Rho family may have an important role in tumour formation.

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Year:  1996        PMID： 8909807

Source DB:  PubMed          Journal:  Cancer Surv        ISSN： 0261-2429


  12 in total

1.  Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases.

Authors:  E Li; D Stupack; G M Bokoch; G R Nemerow
Journal:  J Virol       Date:  1998-11       Impact factor: 5.103

2.  The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q.

Authors:  A Borkhardt; S Bojesen; O A Haas; U Fuchs; D Bartelheimer; I F Loncarevic; R M Bohle; J Harbott; R Repp; U Jaeger; S Viehmann; T Henn; P Korth; D Scharr; F Lampert
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-01       Impact factor: 11.205

3.  Human RhoA/RhoGDI complex expressed in yeast: GTP exchange is sufficient for translocation of RhoA to liposomes.

Authors:  P W Read; X Liu; K Longenecker; C G Dipierro; L A Walker; A V Somlyo; A P Somlyo; R K Nakamoto
Journal:  Protein Sci       Date:  2000-02       Impact factor: 6.725

Review 4.  Interplay between FAK, PKCδ, and p190RhoGAP in the regulation of endothelial barrier function.

Authors:  Katie L Grinnell; Elizabeth O Harrington
Journal:  Microvasc Res       Date:  2011-04-22       Impact factor: 3.514

5.  Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.

Authors:  W Du; P F Lebowitz; G C Prendergast
Journal:  Mol Cell Biol       Date:  1999-03       Impact factor: 4.272

Review 6.  Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.

Authors:  D I Johnson
Journal:  Microbiol Mol Biol Rev       Date:  1999-03       Impact factor: 11.056

7.  Regulatory models of RhoA suppression by dematin, a cytoskeletal adaptor protein.

Authors:  Morvarid Mohseni; Athar H Chishti
Journal:  Cell Adh Migr       Date:  2009-04-07       Impact factor: 3.405

8.  The small GTPase RhoA, but not Rac1, is essential for conditioned aversive memory formation through regulation of actin rearrangements in rat dorsal hippocampus.

Authors:  Jun Wang; Yu-hua Wang; Yuan-yuan Hou; Tao Xi; Yao Liu; Jing-gen Liu
Journal:  Acta Pharmacol Sin       Date:  2013-04-08       Impact factor: 6.150

9.  Requirement of p21-activated kinase (PAK) for Salmonella typhimurium-induced nuclear responses.

Authors:  L M Chen; S Bagrodia; R A Cerione; J E Galán
Journal:  J Exp Med       Date:  1999-05-03       Impact factor: 14.307

10.  RHOG Activates RAC1 through CDC42 Leading to Tube Formation in Vascular Endothelial Cells.

Authors:  Oula El Atat; Amira Fakih; Mirvat El-Sibai
Journal:  Cells       Date:  2019-02-18       Impact factor: 6.600
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