| Literature DB >> 890895 |
Abstract
The Jaffé reaction for creatinine assay appears to follow pseudo-first-order kinetics; first-order rate constants are different for different samples. Rate constants for 10 different serum samples varied from a low value of 0.0040 +/- 0.0003 s-1 to 0.0084 +/- 0.0008 s-1. We describe an approach for determining first-order rate constants from kinetic data and discuss the effects of the above observations on the mathematical formulations required for reliable kinetic determinations of creatinine.Entities:
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Year: 1977 PMID: 890895
Source DB: PubMed Journal: Clin Chem ISSN: 0009-9147 Impact factor: 8.327