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Literature DB >> 8907019

Protective effects of GSH, vitamin E, and selenium on lipid peroxidation in cadmium-fed rats.

Abstract

Increased intake of Cd results in its retention and in peroxidative damage in soft tissues. Coadministration of antioxidants, viz., glutathione (GSH), alpha-tocopherol, and Se, restricted the uptake and distribution of Cd in liver and kidney of rats. Moreover, no rise in malondialdehyde was recorded. Although possible antioxidative mechanisms manifested by GSH, alpha-tocopherol, and Se have been discussed, it is hypothesized that GSH functions as a Cd chelator. Glutathione yielded favorable effects in comparison to Se and alpha-tocopherol.

Entities: Chemical Species

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Year: 1996 PMID： 8907019 DOI： 10.1007/BF02785435

Source DB: PubMed Journal: Biol Trace Elem Res ISSN： 0163-4984 Impact factor: 3.738

28 in total

1. Antiperoxidative mechanisms offered by selenium against liver injury caused by cadmium and mercury in rat.

Authors: S V Rana; P R Boora
Journal: Bull Environ Contam Toxicol Date: 1992-01 Impact factor: 2.151

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Authors: S Horiuchi; M Inoue; Y Morino
Journal: Eur J Biochem Date: 1978-07-03

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Authors: J S Cornell; A Meister
Journal: Proc Natl Acad Sci U S A Date: 1976-02 Impact factor: 11.205

4. Correlation of hepatic metallothionein concentrations with acute cadmium toxicity in the mouse.

Authors: G S Probst; W F Bousquet; T S Miya
Journal: Toxicol Appl Pharmacol Date: 1977-01 Impact factor: 4.219

5. Formation and possible role of bis(methylmercuric) selenide in rats treated with methylmercury and selenite.

Authors: T Masukawa; H Kito; M Hayashi; H Iwata
Journal: Biochem Pharmacol Date: 1982-01-01 Impact factor: 5.858

6. The amelioration of cadmium-induced injury in isolated hepatocytes by reduced glutathione.

Authors: N H Stacey
Journal: Toxicology Date: 1986-12-01 Impact factor: 4.221

7. Antioxidant protection of phospholipid bilayers by alpha-tocopherol. Control of alpha-tocopherol status and lipid peroxidation by ascorbic acid and glutathione.

Authors: D C Liebler; D S Kling; D J Reed
Journal: J Biol Chem Date: 1986-09-15 Impact factor: 5.157

8. Biliary excretion of cadmium by rats: effects of zinc, cadmium, and selenium pretreatments.

Authors: H D Stowe
Journal: J Toxicol Environ Health Date: 1976-09

9. Glutathione peroxidase and catalase in liver, kidney, testis and brain regions of rats following cadmium exposure and subsequent withdrawal.

Authors: G S Shukla; T Hussain; R S Srivastava; S V Chandra
Journal: Ind Health Date: 1989 Impact factor: 2.179

Review 10. Cell calcium, vitamin E, and the thiol redox system in cytotoxicity.

Authors: G A Pascoe; D J Reed
Journal: Free Radic Biol Med Date: 1989 Impact factor: 7.376

14 in total

1. Effects of selenium and silicon on enhancing antioxidative capacity in ramie (Boehmeria nivea (L.) Gaud.) under cadmium stress.

Authors: Hui Tang; Yunguo Liu; Xiaomin Gong; Guangming Zeng; Bohong Zheng; Dafei Wang; Zhichao Sun; Lu Zhou; Xiaoxia Zeng
Journal: Environ Sci Pollut Res Int Date: 2015-02-11 Impact factor: 4.223

2. Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung.

Authors: Xin Hu; Joshua D Chandler; Jolyn Fernandes; Michael L Orr; Li Hao; Karan Uppal; David C Neujahr; Dean P Jones; Young-Mi Go
Journal: Biochim Biophys Acta Gen Subj Date: 2018-04-12 Impact factor: 3.770

3. Neuro- and nephrotoxicity of subchronic cadmium chloride exposure and the potential chemoprotective effects of selenium nanoparticles.

Authors: Kadry M Sadek; Mohamed A Lebda; Tarek K Abouzed; Sherif M Nasr; Moustafa Shoukry
Journal: Metab Brain Dis Date: 2017-06-28 Impact factor: 3.584

Protective effects of GSH, vitamin E, and selenium on lipid peroxidation in cadmium-fed rats.

1. Antiperoxidative mechanisms offered by selenium against liver injury caused by cadmium and mercury in rat.

2. Gamma-glutamyl transpeptidase: sidedness of its active site on renal brush-border membrane.

3. Glutathione and gamma-glutamyl cycle enzymes in crypt and villus tip cells of rat jejunal mucosa.

4. Correlation of hepatic metallothionein concentrations with acute cadmium toxicity in the mouse.

5. Formation and possible role of bis(methylmercuric) selenide in rats treated with methylmercury and selenite.

6. The amelioration of cadmium-induced injury in isolated hepatocytes by reduced glutathione.

7. Antioxidant protection of phospholipid bilayers by alpha-tocopherol. Control of alpha-tocopherol status and lipid peroxidation by ascorbic acid and glutathione.

8. Biliary excretion of cadmium by rats: effects of zinc, cadmium, and selenium pretreatments.

9. Glutathione peroxidase and catalase in liver, kidney, testis and brain regions of rats following cadmium exposure and subsequent withdrawal.

Review 10. Cell calcium, vitamin E, and the thiol redox system in cytotoxicity.

1. Effects of selenium and silicon on enhancing antioxidative capacity in ramie (Boehmeria nivea (L.) Gaud.) under cadmium stress.

2. Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung.

3. Neuro- and nephrotoxicity of subchronic cadmium chloride exposure and the potential chemoprotective effects of selenium nanoparticles.

4. Therapeutic efficacy of chlorogenic acid on cadmium-induced oxidative neuropathy in a murine model.

5. Neuroprotective efficiency of Mangifera indica leaves extract on cadmium-induced cortical damage in rats.

6. Influence of N-acetylcysteine on renal toxicity of cadmium in rats.

7. Assessment of sulforaphane-induced protective mechanisms against cadmium toxicity in human mesenchymal stem cells.

8. Should autism be considered a canary bird telling that Homo sapiens may be on its way to extinction?

9. Preventive effects of β-cryptoxanthin against cadmium-induced oxidative stress in the rat testis.

10. Protective effects of Korean red ginseng extract on cadmium-induced hepatic toxicity in rats.