Literature DB >> 8905162

The use of lithium in the treatment of aggressive behaviours with two brain-injured individuals in a state psychiatric hospital.

S B Bellus1, D Stewart, J G Vergo, P P Kost, J Grace, S R Barkstrom.   

Abstract

Brain-injured individuals often experience problems with aggression which can prevent full community reintegration. Two cases involving individuals (one 4 years, one 17 years post-injury) who had been placed in a state psychiatric hospital due to aggressive and/or self-injurious behaviours are discussed. Utilizing medication dosages and behavioural acuity indicators over a 2 year period, the authors demonstrate the efficacy of lithium carbonate in treating aggressive behaviours. Lithium, in concert with other medications, not only led to a decrease in the frequency of aggressive outbursts and in the need for restrictive and costly behaviour control techniques, but also allowed for a significant reduction in the use of neuroleptic medication in one case. The authors conclude that the use of lithium, within the context of an intensive, behavioural rehabilitation programme, may yield positive effects in the control of aggressive behaviour even in long-term post-injury cases.

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Year:  1996        PMID: 8905162     DOI: 10.1080/026990596123954

Source DB:  PubMed          Journal:  Brain Inj        ISSN: 0269-9052            Impact factor:   2.311


  6 in total

Review 1.  Common psychiatric syndromes and pharmacologic treatments of traumatic brain injury.

Authors:  L A Labbate; D L Warden
Journal:  Curr Psychiatry Rep       Date:  2000-06       Impact factor: 5.285

2.  Management of Psychiatric Disorders in Patients with Stroke and Traumatic Brain Injury.

Authors:  Gautam Saha; Kaustav Chakraborty; Amrit Pattojoshi
Journal:  Indian J Psychiatry       Date:  2022-03-23       Impact factor: 2.983

3.  Effects of lithium on aggression in Drosophila.

Authors:  Rencong Wang; Baoxu Ma; Kai Shi; Fengming Wu; Chuan Zhou
Journal:  Neuropsychopharmacology       Date:  2022-10-17       Impact factor: 8.294

Review 4.  Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup.

Authors:  Ramon Diaz-Arrastia; Patrick M Kochanek; Peter Bergold; Kimbra Kenney; Christine E Marx; Col Jamie B Grimes; L T C Yince Loh; L T C Gina E Adam; Devon Oskvig; Kenneth C Curley; Wanda Salzer
Journal:  J Neurotrauma       Date:  2014-01-15       Impact factor: 5.269

5.  The neurobiological bases for development of pharmacological treatments of aggressive disorders.

Authors:  Allan Siegel; Suresh Bhatt; Rekha Bhatt; Steven S Zalcman
Journal:  Curr Neuropharmacol       Date:  2007       Impact factor: 7.363

6.  Neuropsychiatric Aspects of Traumatic Brain Injury.

Authors: 
Journal:  Curr Treat Options Neurol       Date:  2000-03       Impact factor: 3.972

  6 in total

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