Literature DB >> 8902542

Vitamin C: antioxidant or pro-oxidant in vivo?

B Halliwell1.   

Abstract

Ascorbic acid has a multiplicity of antioxidant properties, but it can exert pro-oxidant effects in vitro, usually by interaction with transition metal ions. It is as yet uncertain that these pro-oxidant effects have any biological relevance: some of the available data are summarized.

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Year:  1996        PMID： 8902542     DOI： 10.3109/10715769609149066

Source DB:  PubMed          Journal:  Free Radic Res        ISSN： 1029-2470


  78 in total

1.  Effects of clarification on physicochemical characteristics, antioxidant capacity and quality attributes of açaí (Euterpe oleracea Mart.) juice.

Authors:  Leiliane Teles Cesar; Marília de Freitas Cabral; Geraldo Arraes Maia; Raimundo Wilane de Figueiredo; Maria Raquel Alcântara de Miranda; Paulo Henrique Machado de Sousa; Isabella Montenegro Brasil; Carmen Luiza Gomes
Journal:  J Food Sci Technol       Date:  2012-09-16       Impact factor: 2.701

2.  Distinct oxidative cleavage and modification of bovine [Cu- Zn]-SOD by an ascorbic acid/Cu(II) system: Identification of novel copper binding site on SOD molecule.

Authors:  Hiroshi Uehara; Shen Luo; Baikuntha Aryal; Rodney L Levine; V Ashutosh Rao
Journal:  Free Radic Biol Med       Date:  2016-02-10       Impact factor: 7.376

Review 3.  Targeting cancer vulnerabilities with high-dose vitamin C.

Authors:  Bryan Ngo; Justin M Van Riper; Lewis C Cantley; Jihye Yun
Journal:  Nat Rev Cancer       Date:  2019-05       Impact factor: 60.716

4.  Blood transfusion increases radical promoting non-transferrin bound iron in preterm infants.

Authors:  K Hirano; T Morinobu; H Kim; M Hiroi; R Ban; S Ogawa; H Ogihara; H Tamai; T Ogihara
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2001-05       Impact factor: 5.747

5.  Uric acid inhibits placental system A amino acid uptake.

Authors:  S A Bainbridge; F von Versen-Höynck; J M Roberts
Journal:  Placenta       Date:  2008-12-05       Impact factor: 3.481

6.  Neuroprotective molecular mechanisms of (-)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties.

Authors:  Orly Weinreb; Tamar Amit; Silvia Mandel; Moussa B H Youdim
Journal:  Genes Nutr       Date:  2009-09-10       Impact factor: 5.523

7.  Reply to Yew et al., "Vitamin C and Mycobacterium tuberculosis Persisters".

Authors:  Catherine Vilchèze; William R Jacobs
Journal:  Antimicrob Agents Chemother       Date:  2018-10-24       Impact factor: 5.191

8.  Availability of non-carotenoid antioxidants affects the expression of a carotenoid-based sexual ornament.

Authors:  Thomas W Pike; Jonathan D Blount; Jan Lindström; Neil B Metcalfe
Journal:  Biol Lett       Date:  2007-08-22       Impact factor: 3.703

9.  Ascorbate compartmentalization in the CNS.

Authors:  M E Rice
Journal:  Neurotox Res       Date:  1999-12       Impact factor: 3.911

10.  Implications for degenerative disorders: antioxidative activity, total phenols, flavonoids, ascorbic acid, beta-carotene and beta-tocopherol in Aloe vera.

Authors:  Nurten Ozsoy; Eda Candoken; Nuriye Akev
Journal:  Oxid Med Cell Longev       Date:  2009 Apr-Jun       Impact factor: 6.543
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