Literature DB >> 890235

A radioprotective effect of vitamin C observed in Chinese hamster ovary cells.

M K O'Connor, J F Malone, M Moriarty, S Mulgrew.   

Abstract

Vitamin C at high concentrations was found to inhibit the growth of CHO clone A cells in culture. It had a radioprotective effect, giving a maximum increase in cell survival of a factor of seven under the experimental conditions used. The protective effect was mainly but not exclusively attributable to an increase in the Do, the maximum increase observed being the order of 1.4.

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Year:  1977        PMID: 890235     DOI: 10.1259/0007-1285-50-596-587

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  5 in total

1.  High Levels of Dietary Supplement Vitamins A, C and E are Absorbed in the Small Intestine and Protect Nutrient Transport Against Chronic Gamma Irradiation.

Authors:  Marjolaine Roche; Prasad V S V Neti; Francis W Kemp; Edouard I Azzam; Ronaldo P Ferraris; Roger W Howell
Journal:  Radiat Res       Date:  2015-10-20       Impact factor: 2.841

2.  Effect of radiotherapy on plasma and tumour ascorbic acid levels.

Authors:  M J Moriarty; S Mulgrew; J F Malone; C Mothersill
Journal:  Ir J Med Sci       Date:  1980-06       Impact factor: 1.568

3.  Some effects of administration of large doses of vitamin C in patients with skin carcinoma.

Authors:  M Moriarty; S Mulgrew; C Mothersill; J F Malone; M Hatch
Journal:  Ir J Med Sci       Date:  1978-05       Impact factor: 1.568

4.  RelB Expression Determines the Differential Effects of Ascorbic Acid in Normal and Cancer Cells.

Authors:  Xiaowei Wei; Yong Xu; Fang Fang Xu; Luksana Chaiswing; David Schnell; Teresa Noel; Chi Wang; Jinfei Chen; Daret K St Clair; William H St Clair
Journal:  Cancer Res       Date:  2017-01-20       Impact factor: 12.701

Review 5.  Space Radiation Biology for "Living in Space".

Authors:  Satoshi Furukawa; Aiko Nagamatsu; Mitsuru Nenoi; Akira Fujimori; Shizuko Kakinuma; Takanori Katsube; Bing Wang; Chizuru Tsuruoka; Toshiyuki Shirai; Asako J Nakamura; Asako Sakaue-Sawano; Atsushi Miyawaki; Hiroshi Harada; Minoru Kobayashi; Junya Kobayashi; Takekazu Kunieda; Tomoo Funayama; Michiyo Suzuki; Tatsuo Miyamoto; Jun Hidema; Yukari Yoshida; Akihisa Takahashi
Journal:  Biomed Res Int       Date:  2020-04-08       Impact factor: 3.411

  5 in total

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