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Literature DB >> 890160

Influence of DDT, DDVP and malathion on FSH, LH and testosterone serum levels and testosterone concentration in testis.

Abstract

Groups of adult male rats were treated with DDT, DDVP or malathion orally for two or three weeks. Body weight and testis weight did not change. FSH and LH levels in serum also remained unchanged, whereas that of testosterone was decreased by DDT. This substance also diminished the concentration of testosterone in the testis. Therefore, the previously observed damage to spermatogenesis by DDT are assumed to be caused by a lack of androgens. Those following treatment with DDVP or malathion seem to be due to a direct cytotoxic effect.

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Year: 1977 PMID： 890160 DOI： 10.1007/bf01686072

Source DB: PubMed Journal: Bull Environ Contam Toxicol ISSN： 0007-4861 Impact factor: 2.151

6 in total

1. Alterations of the seminiferous epithelium and the Leydig cells of the mouse testis after the application of dichlorvos (DDVP).

Authors: W Krause; S Homola
Journal: Bull Environ Contam Toxicol Date: 1974-05 Impact factor: 2.151

Review 2. Influence of chlorinated hydrocarbons and organophosphate insecticides on metabolism of steroids.

Authors: D Kupfer
Journal: Ann N Y Acad Sci Date: 1969 Impact factor: 5.691

3. DDT homologues: estrogen-like effects on the vagina, uterus and pituitary of the rat.

Authors: R J Gellert; W L Heinrichs; R S Swerdloff
Journal: Endocrinology Date: 1972-10 Impact factor: 4.736

4. Zinc-DDT interrelationships in growth and reproduction in the rat.

Authors: J P Feaster; C H Van Middelem; G K Davis
Journal: J Nutr Date: 1972-04 Impact factor: 4.798

5. FSH and testosterone levels in the plasma of juvenile male rats after application of ovine FSH, HCG and PMS at different ages.

Authors: W Krause; P Schwaebe
Journal: Endokrinologie Date: 1976-10

6. The effect of DDT on spermatogenesis of the juvenile rat.

Authors: W Krause; K Hamm; J Weissmüller
Journal: Bull Environ Contam Toxicol Date: 1975-08 Impact factor: 2.151

6 in total

1. Exogenous arachidonate restores the dimethoate-induced inhibition of steroidogenesis in rat interstitial cells.

Authors: Mariana Astiz; Graciela Hurtado de Catalfo; María J T de Alaniz; Carlos Alberto Marra
Journal: Lipids Date: 2012-04-03 Impact factor: 1.880

2. Subacute administration of organophosphorus pesticides and hepatic drug metabolizing enzyme activity in normal and malnourished rats.

Authors: S Bulusu; I Chakravarty
Journal: Bull Environ Contam Toxicol Date: 1986-01 Impact factor: 2.151

6. Disruption of steroidogenesis after dimethoate exposure and efficacy of N-acetylcysteine in rats: an old drug with new approaches.

Authors: Manel Jallouli; Ines El Bini Dhouib; Hanène Dhouib; Montassar Lasram; Najoua Gharbi; Saloua El Fazaa
Journal: Environ Sci Pollut Res Int Date: 2016-01-15 Impact factor: 4.223

6 in total

Influence of DDT, DDVP and malathion on FSH, LH and testosterone serum levels and testosterone concentration in testis.

1. Alterations of the seminiferous epithelium and the Leydig cells of the mouse testis after the application of dichlorvos (DDVP).

Review 2. Influence of chlorinated hydrocarbons and organophosphate insecticides on metabolism of steroids.

3. DDT homologues: estrogen-like effects on the vagina, uterus and pituitary of the rat.

4. Zinc-DDT interrelationships in growth and reproduction in the rat.

5. FSH and testosterone levels in the plasma of juvenile male rats after application of ovine FSH, HCG and PMS at different ages.

6. The effect of DDT on spermatogenesis of the juvenile rat.

1. Exogenous arachidonate restores the dimethoate-induced inhibition of steroidogenesis in rat interstitial cells.

2. Subacute administration of organophosphorus pesticides and hepatic drug metabolizing enzyme activity in normal and malnourished rats.

3. Paraoxon inhibits fertilization of mouse gametes in vitro.

4. Involvement of lipids in dimethoate-induced inhibition of testosterone biosynthesis in rat interstitial cells.

5. Accumulation of polychlorinated biphenyls in steroidgenic tissue of gonads and adrenals in Japanese quail.

6. Disruption of steroidogenesis after dimethoate exposure and efficacy of N-acetylcysteine in rats: an old drug with new approaches.