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Literature DB >> 8901113

Plasma N tau-methylhistidine concentration is a sensitive index of myofibrillar protein degradation during starvation in rats.

Abstract

Urinary excretion of N tau-methylhistidine (MeHis) in rats was linearly elevated by starvation for 2 days. Plasma concentration of MeHis on day 1 and day 2 of starvation were increased 2.4- and 2.6-fold, respectively. The amount of released MeHis from the isolated muscles into medium during a 2-h incubation period was increased with starvation corresponded to the plasma MeHis concentration. The results of this study suggest that plasma MeHis is a sensitive index of myofibrillar protein degradation.

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Year: 1996 PMID： 8901113 DOI： 10.1271/bbb.60.501

Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043

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