Literature DB >> 890042

In situ observation of dense-body release from hydrated human platelets.

J L Costa.   

Abstract

Human-platelet dense bodies (secretory granules) have been visualized by electron microscopy in cells maintained in a hydrated state, and their sequential release after stimulation by thrombin has been observed in situ. The pattern of dense body release from individual platelets suggests that a a portion of the dense body complement of a single cell can be extruded without appreciable change in the position of the remaining dense bodies.

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Year:  1977        PMID: 890042      PMCID: PMC1473329          DOI: 10.1016/S0006-3495(77)85590-2

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  13 in total

1.  Platelet 5-HT uptake and release stopped rapidly by formaldehyde.

Authors:  J L Costa; D L Murphy
Journal:  Nature       Date:  1975-05-29       Impact factor: 49.962

2.  Further observations on the effect of anoxia on histamine release from guinea-pig and rat lung tissue in vitro.

Authors:  B DIAMANT
Journal:  Acta Physiol Scand       Date:  1962-09

3.  Stimulus-secretion coupling in platelets. Effects of drugs on secretion on adenosine 5'-triphosphate.

Authors:  F Friedman; T C Detwiler
Journal:  Biochemistry       Date:  1975-03-25       Impact factor: 3.162

4.  Changes in human-platelet storage packet size following incubation with labelled serotonin.

Authors:  J L Costa; D L Murphy
Journal:  Life Sci       Date:  1976-06-15       Impact factor: 5.037

5.  Direct measurement of membrane motion and fluidity by electron microscopy.

Authors:  S W Hui
Journal:  Nature       Date:  1976-07-22       Impact factor: 49.962

6.  Quantitative evaluation of the loss of human platelet dense bodies following stimulation by thrombin or A23187.

Authors:  J L Costa; T C Detwiler; R D Feinman; D L Murphy; C S Patlak; K D Pettigrew
Journal:  J Physiol       Date:  1977-01       Impact factor: 5.182

7.  Origin and function of platelet dense bodies.

Authors:  J G White
Journal:  Ser Haematol       Date:  1970

8.  The ultrastructure of negatively stained platelets. Some physiologic implications.

Authors:  B S Bull
Journal:  Blood       Date:  1966-12       Impact factor: 22.113

9.  The dense bodies of human platelets: inherent electron opacity of the serotonin storage particles.

Authors:  J G White
Journal:  Blood       Date:  1969-04       Impact factor: 22.113

10.  Demonstration and evaluation of apparent cytoplasmic and vesicular serotonin compartments in human platelets.

Authors:  J L Costa; D L Murphy; M S Kafka
Journal:  Biochem Pharmacol       Date:  1977-03-15       Impact factor: 5.858

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  1 in total

1.  Transformation and motility of human platelets: details of the shape change and release reaction observed by optical and electron microscopy.

Authors:  R D Allen; L R Zacharski; S T Widirstky; R Rosenstein; L M Zaitlin; D R Burgess
Journal:  J Cell Biol       Date:  1979-10       Impact factor: 10.539

  1 in total

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