Literature DB >> 8899962

Large clostridial cytotoxins--a family of glycosyltransferases modifying small GTP-binding proteins.

C von Eichel-Streiber1, P Boquet, M Sauerborn, M Thelestam.   

Abstract

Some Clostridium species produce ABX-type protein cytotoxins of high molecular weight. These toxins constitute the group of large clostridial cytotoxins (LCTs), which have homologous protein sequences, exert glycosyltransferase activity and modify GTP-binding proteins of the Ras-superfamily. These characteristics render the LCTs valuable tools for developmental and cell biologists.

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Year:  1996        PMID： 8899962     DOI： 10.1016/0966-842X(96)10061-5

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  69 in total

1.  Synergistic activation of JNK/SAPK by interleukin-1 and platelet-derived growth factor is independent of Rac and Cdc42.

Authors:  W Davis; L R Stephens; P T Hawkins; J Saklatvala
Journal:  Biochem J       Date:  1999-03-01       Impact factor: 3.857

Review 2.  Clostridial toxins: molecular probes of Rho-dependent signaling and apoptosis.

Authors:  D A Bobak
Journal:  Mol Cell Biochem       Date:  1999-03       Impact factor: 3.396

3.  Patterns of sequence conservation in the S-Layer proteins and related sequences in Clostridium difficile.

Authors:  Emanuela Calabi; Neil Fairweather
Journal:  J Bacteriol       Date:  2002-07       Impact factor: 3.490

4.  Integration of metabolism and virulence by Clostridium difficile CodY.

Authors:  Sean S Dineen; Shonna M McBride; Abraham L Sonenshein
Journal:  J Bacteriol       Date:  2010-08-13       Impact factor: 3.490

Review 5.  Clostridium difficile associated diarrhoea: diagnosis and treatment.

Authors:  John Starr
Journal:  BMJ       Date:  2005-09-03

6.  Detection of toxB, a plasmid virulence gene of Escherichia coli O157, in enterohemorrhagic and enteropathogenic E. coli.

Authors:  Rosangela Tozzoli; Alfredo Caprioli; Stefano Morabito
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

7.  Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor.

Authors:  N Mani; B Dupuy
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-24       Impact factor: 11.205

8.  Toxins, butyric acid, and other short-chain fatty acids are coordinately expressed and down-regulated by cysteine in Clostridium difficile.

Authors:  S Karlsson; A Lindberg; E Norin; L G Burman; T Akerlund
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

9.  Molecular analysis of the pathogenicity locus and polymorphism in the putative negative regulator of toxin production (TcdC) among Clostridium difficile clinical isolates.

Authors:  Patrizia Spigaglia; Paola Mastrantonio
Journal:  J Clin Microbiol       Date:  2002-09       Impact factor: 5.948

10.  Translocation of Clostridium difficile toxin B across polarized Caco-2 cell monolayers is enhanced by toxin A.

Authors:  Tim Du; Michelle J Alfa
Journal:  Can J Infect Dis       Date:  2004-03
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