Literature DB >> 889855

Rat heart in culture as a tool to elucidate the cellular origin of lipoprotein lipase.

T Chajek, O Stein, Y Stein.   

Abstract

Lipoprotein lipase was determined in 5-day old cell cultures derived from hearts of newborn rats. With the help of the preplating method the cells were subdivided into cultures containing predominantly cardiac myocytes and into those composed mainly of mesenchymal cells. Lipoprotein lipase activity, associated with the mesenchymal cells was ten times higher than the activity found in the cultures containing mainly the myogenic cells. It is suggested that the mesenchymal cells are the progenitors of lipoprotein lipase in rat heart.

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Year:  1977        PMID: 889855     DOI: 10.1016/0005-2760(77)90131-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  5 in total

1.  Cytochrome P450 mono-oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat.

Authors:  T Thum; J Borlak
Journal:  Br J Pharmacol       Date:  2000-08       Impact factor: 8.739

2.  Characterization of triacylglycerol hydrolase activities in isolated myocardial cells from rat heart.

Authors:  I Ramírez; A J Kryski; O Ben-Zeev; M C Schotz; D L Severson
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857

3.  Effect of diabetes on acid and neutral triacylglycerol lipase and on lipoprotein lipase activities in isolated myocardial cells from rat heart.

Authors:  I Ramírez; D L Severson
Journal:  Biochem J       Date:  1986-08-15       Impact factor: 3.857

4.  Differences in the metabolism of very-low-density lipoproteins by isolated beating-heart cells and the isolated perfused rat heart. Evidence for collagenase-released extracellular lipoprotein lipase.

Authors:  O V Rajaram; M G Clark; P J Barter
Journal:  Biochem J       Date:  1980-02-15       Impact factor: 3.857

5.  Lipoprotein lipase activity of rat cardiac muscle. Changes in the enzyme activity during incubations of isolated cardiac-muscle cells in vitro.

Authors:  P Chohan; A Cryer
Journal:  Biochem J       Date:  1980-03-15       Impact factor: 3.857

  5 in total

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