Literature DB >> 8898427

Somatostatin in the treatment of gastrointestinal bleeding caused by angiodysplasia.

M R Andersen1, J Aaseby.   

Abstract

BACKGROUND: Bleeding due to gastrointestinal angiodysplasia is occasionally very difficult to treat by conventional means.
METHODS: A 37-year-old woman with recurrent anemia caused by angiodysplasia was treated with a somatostatin analogue, given at a dose of 100 micrograms subcutaneously twice daily.
RESULTS: After 26 months of treatment the patient was without any signs or symptoms of bleeding from her gastrointestinal angiodysplasia.
CONCLUSIONS: Somatostatin may be efficacious in the treatment of gastrointestinal bleeding due to angiodysplasia. Further investigation is needed.

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Year:  1996        PMID: 8898427     DOI: 10.3109/00365529609003126

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  9 in total

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Review 2.  Pharmacological therapy of vascular malformations of the gastrointestinal tract.

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4.  Comparison Between Intravenous and Intramuscular Octreotide in the Management of Heyde's Syndrome.

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5.  New endoscopic techniques for obscure gastrointestinal bleeding.

Authors:  Henk den Ouden; S A C van Tuyl; Marcel Groenen; Mark F J Stolk; Ernst J Kuipers
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Review 6.  Aortic stenosis and anemia with an update on approaches to managing angiodysplasia in 2018.

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Review 7.  von Willebrand factor regulation of blood vessel formation.

Authors:  Anna M Randi; Koval E Smith; Giancarlo Castaman
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8.  Radiofrequency ablation using Barrx® for the endoscopic treatment of gastric antral vascular ectasia: a series of three cases and a review of the literature on treatment options.

Authors:  Anish Patel; Sunil Patel; Prasanna C Wickremesinghe; Deepak Vadada
Journal:  Clin Exp Gastroenterol       Date:  2017-07-10

9.  Efficacy and safety of pasireotide-LAR for the treatment of refractory bleeding due to gastrointestinal angiodysplasias: results of the ANGIOPAS multicenter phase II noncomparative prospective double-blinded randomized study.

Authors:  Robert Benamouzig; Mourad Benallaoua; Jean-Christophe Saurin; Marouane Boubaya; Christophe Cellier; René Laugier; Magalie Vincent; Christian Boustière; Rodica Gincul; Elia Samaha; Philippe Grandval; Thomas Aparicio; Gheorghe Airinei; Bakhtiar Bejou; Cyriaque Bon; Jean-Jacques Raynaud; Vincent Levy; Denis Sautereau
Journal:  Therap Adv Gastroenterol       Date:  2018-02-16       Impact factor: 4.409

  9 in total

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