BACKGROUND: Glaucoma and cataract are multifactorial diseases. They have been described to be associated with cardiovascular risk factors. METHODS: Twenty-four-hour ECG monitoring was done in 22 normal-tension glaucoma patients, 27 open-angle glaucoma patients, 25 cataract patients, and 20 normal controls. The frequency of silent myocardial ischemia (SMI) as well as that of ventricular extrasystoles (VES) was evaluated. RESULTS: At least one episode of significant asymptomatic ST-T segment depression occurred in 45% of the normal-tension glaucomas, in 25.9% of open-angle glaucomas, in 12% of cataract patients, and in 5% of normal controls. The frequency of VES was not significantly different among the groups. CONCLUSIONS: Glaucoma, especially normal-tension glaucoma, is significantly associated with the occurrence of episodic asymptomatic myocardial ischemias. Cataract patients, however, had only a slightly, statistically not significantly increased frequency of both SMI and VES compared with normals.
BACKGROUND:Glaucoma and cataract are multifactorial diseases. They have been described to be associated with cardiovascular risk factors. METHODS: Twenty-four-hour ECG monitoring was done in 22 normal-tension glaucomapatients, 27 open-angle glaucomapatients, 25 cataractpatients, and 20 normal controls. The frequency of silent myocardial ischemia (SMI) as well as that of ventricular extrasystoles (VES) was evaluated. RESULTS: At least one episode of significant asymptomatic ST-T segment depression occurred in 45% of the normal-tension glaucomas, in 25.9% of open-angle glaucomas, in 12% of cataractpatients, and in 5% of normal controls. The frequency of VES was not significantly different among the groups. CONCLUSIONS:Glaucoma, especially normal-tension glaucoma, is significantly associated with the occurrence of episodic asymptomatic myocardial ischemias. Cataractpatients, however, had only a slightly, statistically not significantly increased frequency of both SMI and VES compared with normals.
Authors: Maneli Mozaffarieh; Daniela Hauenstein; Andreas Schoetzau; Katarzyna Konieczka; Josef Flammer Journal: Mol Vis Date: 2010-03-23 Impact factor: 2.367
Authors: Josef Flammer; Katarzyna Konieczka; Rosa M Bruno; Agostino Virdis; Andreas J Flammer; Stefano Taddei Journal: Eur Heart J Date: 2013-02-10 Impact factor: 29.983