Literature DB >> 889646

Determination of MAC for halothane, cyclopropane and ether in the rabbit.

J E MacKenzie.   

Abstract

Rabbits have a high rate of ventilation which makes it difficult to obtain a sample of end-tidal gas by the usual procedures. An occlusion technique was developed which provided a gas sample equivalent to an end-tidal gas sample. MAC values were determined using this sampling method. The values obtained +/- SEM were: cyclopropane 15.6 +/- 1.7%, halothane 0.63 +/- 0.06% and ether 2.7 +/- 0.2%.

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Year:  1977        PMID: 889646     DOI: 10.1093/bja/49.4.319

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  1 in total

1.  The cardiovascular effects of cyclopropane in the intact, decerebrate and pithed rabbit preparations.

Authors:  R L Hughes; J E MacKenzie
Journal:  Br J Pharmacol       Date:  1978-01       Impact factor: 8.739

  1 in total

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