Literature DB >> 8895284

A similar incidence of transient neurologic symptoms after spinal anesthesia with 2% and 5% lidocaine.

K F Hampl1, M C Schneider, H Pargger, J Gut, J Drewe, K Drasner.   

Abstract

Recent reports suggest that transient neurologic symptoms are common after spinal anesthesia with 5% lidocaine. To determine whether reducing the anesthetic concentration might decrease the incidence of symptoms, 50 ASA class I or II patients undergoing brief gynecologic procedures under spinal anesthesia were randomly allocated to receive 1 mg/kg of either 5% or 2% lidocaine in 7.5% glucose. Patients were evaluated on the first postoperative day by an anesthesiologist who was unaware of the solution administered or the details of the anesthetic procedure. Symptoms suggestive of transient radicular irritation were observed in 8 patients (32%) receiving 5% lidocaine, and in 10 patients (40%) receiving 2% lidocaine (NS). These results confirm our previous findings that transient neurologic symptoms may occur in up to one third of the patients receiving 5% lidocaine, and indicate that a modest reduction in lidocaine concentration does not reduce risk.

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Year:  1996        PMID: 8895284     DOI: 10.1097/00000539-199611000-00026

Source DB:  PubMed          Journal:  Anesth Analg        ISSN: 0003-2999            Impact factor:   5.108


  14 in total

Review 1.  [Toxicology of local anesthetics. Clinical, therapeutic and pathological mechanisms].

Authors:  W Zink; B M Graf
Journal:  Anaesthesist       Date:  2003-12       Impact factor: 1.041

Review 2.  [Unilateral spinal anesthesia : Literature review and recommendations].

Authors:  B Büttner; A Mansur; M Bauer; J Hinz; I Bergmann
Journal:  Anaesthesist       Date:  2016-11       Impact factor: 1.041

Review 3.  Complications of regional anaesthesia Incidence and prevention.

Authors:  K A Faccenda; B T Finucane
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606

Review 4.  Regional anaesthesia in the elderly: a clinical guide.

Authors:  Ban C H Tsui; Alese Wagner; Brendan Finucane
Journal:  Drugs Aging       Date:  2004       Impact factor: 3.923

5.  Comparison of hyperbaric ropivacaine and hyperbaric bupivacaine in unilateral spinal anaesthesia.

Authors:  Zekiye Bigat; Neval Boztug; Bilge Karsli; Nihan Cete; Ertugrul Ertok
Journal:  Clin Drug Investig       Date:  2006       Impact factor: 2.859

6.  A comparison of intraarticular morphine and bupivacaine for pain control and outpatient status after an arthroscopic knee surgery under a low dose of spinal anaesthesia.

Authors:  Ahmet Eroglu; Sebnem Saracoglu; Engin Erturk; Muge Kosucu; Servet Kerimoglu
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-02-04       Impact factor: 4.342

Review 7.  Benefit and risks of local anesthetics in infants and children.

Authors:  Joel B Gunter
Journal:  Paediatr Drugs       Date:  2002       Impact factor: 3.022

Review 8.  Prilocaine hydrochloride 2% hyperbaric solution for intrathecal injection: a clinical review.

Authors:  Alberto Manassero; Andrea Fanelli
Journal:  Local Reg Anesth       Date:  2017-03-31

9.  Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis.

Authors:  Patrice Forget; Josip A Borovac; Elizabeth M Thackeray; Nathan L Pace
Journal:  Cochrane Database Syst Rev       Date:  2019-12-01

10.  Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis.

Authors:  Hui Li; Junmei Xu; Xin Wang; Guixiu Yuan
Journal:  Mol Med Rep       Date:  2013-11-21       Impact factor: 2.952

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