Literature DB >> 8894570

Molecular epidemiological characteristics of pneumococcal meningitis in children.

R F Kornelisse1, M Sluijter, L Spanjaard, P W Hermans, R de Groot.   

Abstract

The molecular epidemiological characteristics of pneumococcal meningitis in children were studied. Pneumococcal isolates were characterized by serotyping and two genotyping methods, BOX fingerprinting and restriction fragment end labeling, to evaluate whether clonal strains were present within the serotypes or serogroups. During a 17-year period, 68 children admitted to the Sophia Children's Hospital were diagnosed with meningitis due to Streptococcus pneumoniae. Pneumococcal isolates from 44 patients were still available for analysis. All strains were susceptible to penicillin. Serotypes/ serogroups 14, 19, 6, and 18 represented 56% of all isolates. The results of the molecular typing methods demonstrate the absence of clonal relatedness between isolates from patients with pneumococcal meningitis.

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Year:  1996        PMID: 8894570     DOI: 10.1007/bf01691148

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN: 0934-9723            Impact factor:   3.267


  16 in total

1.  Insertion element IS987 from Mycobacterium bovis BCG is located in a hot-spot integration region for insertion elements in Mycobacterium tuberculosis complex strains.

Authors:  P W Hermans; D van Soolingen; E M Bik; P E de Haas; J W Dale; J D van Embden
Journal:  Infect Immun       Date:  1991-08       Impact factor: 3.441

2.  Genomic DNA fingerprinting by restriction fragment end labeling.

Authors:  T J van Steenbergen; S D Colloms; P W Hermans; J de Graaff; R H Plasterk
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205

3.  Evidence for the introduction of a multiresistant clone of serotype 6B Streptococcus pneumoniae from Spain to Iceland in the late 1980s.

Authors:  S Soares; K G Kristinsson; J M Musser; A Tomasz
Journal:  J Infect Dis       Date:  1993-07       Impact factor: 5.226

Review 4.  DNA fingerprinting of Mycobacterium tuberculosis.

Authors:  D van Soolingen; P E de Haas; P W Hermans; J D van Embden
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

5.  Pneumococcal meningitis in children: prognostic indicators and outcome.

Authors:  R F Kornelisse; C M Westerbeek; A B Spoor; B van der Heijde; L Spanjaard; H J Neijens; R de Groot
Journal:  Clin Infect Dis       Date:  1995-12       Impact factor: 9.079

6.  A highly conserved repeated DNA element located in the chromosome of Streptococcus pneumoniae.

Authors:  B Martin; O Humbert; M Camara; E Guenzi; J Walker; T Mitchell; P Andrew; M Prudhomme; G Alloing; R Hakenbeck
Journal:  Nucleic Acids Res       Date:  1992-07-11       Impact factor: 16.971

7.  An epidemic of pneumococcal disease in an overcrowded, inadequately ventilated jail.

Authors:  C W Hoge; M R Reichler; E A Dominguez; J C Bremer; T D Mastro; K A Hendricks; D M Musher; J A Elliott; R R Facklam; R F Breiman
Journal:  N Engl J Med       Date:  1994-09-08       Impact factor: 91.245

8.  Variability of penicillin-binding proteins from penicillin-sensitive Streptococcus pneumoniae.

Authors:  R Hakenbeck; T Briese; L Chalkley; H Ellerbrok; R Kalliokoski; C Latorre; M Leinonen; C Martin
Journal:  J Infect Dis       Date:  1991-08       Impact factor: 5.226

9.  Comparative study of five different DNA fingerprint techniques for molecular typing of Streptococcus pneumoniae strains.

Authors:  P W Hermans; M Sluijter; T Hoogenboezem; H Heersma; A van Belkum; R de Groot
Journal:  J Clin Microbiol       Date:  1995-06       Impact factor: 5.948

10.  Capsular types of Streptococcus pneumoniae isolated from blood and CSF during 1982-1987.

Authors:  S V Nielsen; J Henrichsen
Journal:  Clin Infect Dis       Date:  1992-11       Impact factor: 9.079

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  1 in total

1.  Assessment of molecular typing methods to determine invasiveness and to differentiate clones of Streptococcus pneumoniae.

Authors:  Caroline A Obert; Geli Gao; Jack Sublett; Elaine I Tuomanen; Carlos J Orihuela
Journal:  Infect Genet Evol       Date:  2007-07-27       Impact factor: 3.342

  1 in total

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