A case of parvovirus-B19 adult acute arthritis with some allergic disease clinical features.

A 31-year old woman suddenly presented arthralgias at wrists, knees and feet, swelling of eyelids and the upper lip, itching behind the ears, fever and macular rash on the extensory surface of legs, face and back. Signs and symptoms were strongly suggestive of an allergic reaction but human Parvovirus-B19 serology was positive, IgE serum levels were normal, skin prick tests and RAST for aliments were negative. Joint symptoms and swelling diminished in about four weeks. The relationship between the clinical manifestation of Parvovirus-B19 infection and features of allergic diseases is discussed.