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Literature DB >> 8893808

Sheep CENPB and CENPC genes show a high level of sequence similarity and conserved synteny with their human homologs.

D J Burkin¹, C Jones, H R Burkin, J A McGrew, T E Broad.

Abstract

Sheep CENPB and CENPC clones were isolated from a lung cDNA library. The DNA and predicted amino acid sequences of these clones were compared with their human and mouse homologs and shown to contain a high degree of sequence similarity. Sheep chromosomal assignments were made using a sheep x hamster somatic cell hybrid mini-panel. CENPB was assigned to sheep chromosome 13 and CENPC to chromosome 6. The previously reported assignments of CENPB and CENPC to human chromosomes 20 and 4, respectively, suggest conserved synteny between sheep chromosome 13 and human chromosome 20 and support conserved synteny between sheep chromosome 6 and human chromosome 4.

Entities: Gene Species

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Year: 1996 PMID： 8893808 DOI： 10.1159/000134388

Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171

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Cited

8 in total

1. Nucleotide specificity at the boundary and size requirement of the target sites recognized by human centromere protein B (CENP-B) in vitro.

Authors: K Sugimoto; A Shibata; M Himeno
Journal: Chromosome Res Date: 1998-02 Impact factor: 5.239

2. The distribution of binding sites for centromere protein B (CENP-B) is partly conserved among diverged higher order repeating units of human chromosome 6-specific alphoid DNA.

Authors: K Sugimoto; K Furukawa; K Kusumi; M Himeno
Journal: Chromosome Res Date: 1997-09 Impact factor: 5.239

3. Convergent domestication of pogo-like transposases into centromere-binding proteins in fission yeast and mammals.

Authors: Claudio Casola; Donald Hucks; Cédric Feschotte
Journal: Mol Biol Evol Date: 2007-10-16 Impact factor: 16.240

Review 4. Meiotic CENP-C is a shepherd: bridging the space between the centromere and the kinetochore in time and space.

Authors: Jessica E Fellmeth; Kim S McKim
Journal: Essays Biochem Date: 2020-09-04 Impact factor: 7.258

5. The dimerization domain of PfCENP-C is required for its functions as a centromere protein in human malaria parasite Plasmodium falciparum.

Authors: Garima Verma; Namita Surolia
Journal: Malar J Date: 2014-12-04 Impact factor: 2.979

Sheep CENPB and CENPC genes show a high level of sequence similarity and conserved synteny with their human homologs.

1. Nucleotide specificity at the boundary and size requirement of the target sites recognized by human centromere protein B (CENP-B) in vitro.

2. The distribution of binding sites for centromere protein B (CENP-B) is partly conserved among diverged higher order repeating units of human chromosome 6-specific alphoid DNA.

3. Convergent domestication of pogo-like transposases into centromere-binding proteins in fission yeast and mammals.

Review 4. Meiotic CENP-C is a shepherd: bridging the space between the centromere and the kinetochore in time and space.

5. The dimerization domain of PfCENP-C is required for its functions as a centromere protein in human malaria parasite Plasmodium falciparum.

6. The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation.

7. Lambs with scrapie susceptible genotypes have higher postnatal survival.

8. Adaptive evolution of centromere proteins in plants and animals.