Literature DB >> 8892542

Lung cancer mortality in stainless steel and mild steel welders: a nested case-referent study.

J M Lauritsen1, K S Hansen.   

Abstract

The association between welding and lung cancer has been studied in a nested case-referent study within a cohort of 8,372 metal workers. Lifetime exposure data on welding and other occupational exposures, as well as alcohol and smoking habits, were obtained by interviews of spouses and colleagues. Analysis was based on 439 deceased referents and 94 deceased cases. There was a 70% excess of lung cancer associated with "welding exposure ever" (OR +/- 95% C.I.: 1.68, 1.02-2.78). Overall OR for "mild steel (MS) welding ever" was 1.64, 0.99-2.72. The risk estimates for welding exposures showed an increasing tendency up to 15 years of exposure. The pattern of stainless steel (SS) welding resembles that of mild steel with an estimated OR of 1.65, 0.88-3.0. The general conclusion is that MS welding as well as SS welding seems to be associated with an increased risk of lung cancer. Further followup of the cohort will enhance precision of the estimates.

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Year:  1996        PMID: 8892542     DOI: 10.1002/(SICI)1097-0274(199610)30:4<383::AID-AJIM2>3.0.CO;2-X

Source DB:  PubMed          Journal:  Am J Ind Med        ISSN: 0271-3586            Impact factor:   2.214


  8 in total

1.  Reduction of Biomechanical and Welding Fume Exposures in Stud Welding.

Authors:  Nathan B Fethke; Thomas M Peters; Stephanie Leonard; Mahmoud Metwali; Imali A Mudunkotuwa
Journal:  Ann Occup Hyg       Date:  2015-11-23

Review 2.  Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer.

Authors:  Peter N Lee; Barbara A Forey; Katharine J Coombs
Journal:  BMC Cancer       Date:  2012-09-03       Impact factor: 4.430

3.  Inhalation of iron-abundant gas metal arc welding-mild steel fume promotes lung tumors in mice.

Authors:  L M Falcone; A Erdely; V Kodali; R Salmen; L A Battelli; T Dodd; W McKinney; S Stone; M Donlin; H D Leonard; J L Cumpston; J B Cumpston; R N Andrews; M L Kashon; J M Antonini; P C Zeidler-Erdely
Journal:  Toxicology       Date:  2018-07-25       Impact factor: 4.221

4.  Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice.

Authors:  Patti C Zeidler-Erdely; Michael L Kashon; Shengqiao Li; James M Antonini
Journal:  Respir Res       Date:  2010-06-03

5.  Cancer Risks among Welders and Occasional Welders in a National Population-Based Cohort Study: Canadian Census Health and Environmental Cohort.

Authors:  Jill S MacLeod; M Anne Harris; Michael Tjepkema; Paul A Peters; Paul A Demers
Journal:  Saf Health Work       Date:  2017-01-12

6.  Pulmonary toxicity and lung tumorigenic potential of surrogate metal oxides in gas metal arc welding-stainless steel fume: Iron as a primary mediator versus chromium and nickel.

Authors:  Lauryn M Falcone; Aaron Erdely; Rebecca Salmen; Michael Keane; Lori Battelli; Vamsi Kodali; Lauren Bowers; Aleksandr B Stefaniak; Michael L Kashon; James M Antonini; Patti C Zeidler-Erdely
Journal:  PLoS One       Date:  2018-12-26       Impact factor: 3.240

7.  Exposure to welding fumes increases lung cancer risk among light smokers but not among heavy smokers: evidence from two case-control studies in Montreal.

Authors:  Eric Vallières; Javier Pintos; Jérôme Lavoué; Marie-Élise Parent; Bernard Rachet; Jack Siemiatycki
Journal:  Cancer Med       Date:  2012-06-07       Impact factor: 4.452

8.  Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume.

Authors:  Patti C Zeidler-Erdely; Michael L Kashon; Lori A Battelli; Shih-Houng Young; Aaron Erdely; Jenny R Roberts; Steven H Reynolds; James M Antonini
Journal:  Part Fibre Toxicol       Date:  2008-09-08       Impact factor: 9.400

  8 in total

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