Literature DB >> 8892471

Prism: a new approach to radiotherapy planning software.

I J Kalet1, J P Jacky, M M Austin-Seymour, S M Hummel, K J Sullivan, J M Unger.   

Abstract

PURPOSE: We describe the capabilities and performance of Prism, an innovative new radiotherapy planning system with unusual features and design. The design and implementation strategies are intended to assure high quality and clinical acceptability. The features include Artificial Intelligence tools and special support for multileaf collimator (MLC) systems. The design provides unusual flexibility of operation and ease of expansion. METHODS AND MATERIALS: We have implemented Prism, a three-dimensional (3D) radiotherapy treatment-planning system on standard commercial workstations with the widely available X window system. The design and implementation use ideas taken from recent software engineering research, for example, the use of behavioral entity-relationship modeling and the "Mediator Method" instead of ad-hoc programming. The Prism system includes the usual features of a 3D planning system, including Beam's Eye View and the ability to simulate any treatment geometry possible with any standard radiotherapy accelerator. It includes a rule-based expert system for automated generation of the planning target volume as defined in ICRU Report 50. In addition, it provides special support for planning treatments with a multileaf collimator (MLC). We also implemented a Radiotherapy Treatment Planning Tools Foundation for Prism, so that we are able to use software tools form other institutions without any source code modification.
RESULTS: The Prism system has been in clinical operation at the University of Washington since July 1994 and has been installed at several other clinics. The system is run simultaneously by several users, each with their own workstation operating from a common networked database and software. In addition to the dosimetrists, the system is used by radiation oncologists to define tumor and target volumes and by radiation therapists to select treatment setups to load into a computer controlled accelerator.
CONCLUSIONS: Experience with the installation and operation has shown the design to be effective as both a clinical and research tool. Integration of software tools has eased the development and significantly enhanced the clinical usability of the system. The design has been shown to be a sound basis for further innovation in radiation treatment planning software and for research in the treatment planning process.

Entities:  

Mesh:

Year:  1996        PMID: 8892471     DOI: 10.1016/s0360-3016(96)00322-7

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  10 in total

1.  Anatomical information in radiation treatment planning.

Authors:  I J Kalet; J Wu; M Lease; M M Austin-Seymour; J F Brinkley; C Rosse
Journal:  Proc AMIA Symp       Date:  1999

2.  Head and neck lymph node region delineation with 3-D CT image registration.

Authors:  Chia-Chi Teng; Mary M Austin-Seymour; Jerry Barker; Ira J Kalet; Linda G Shapiro; Mark Whipple
Journal:  Proc AMIA Symp       Date:  2002

3.  A rule-based model for local and regional tumor spread.

Authors:  Ira J Kalet; Mark Whipple; Silvia Pessah; Jerry Barker; Marry M Austin-Seymour; Linda G Shapiro
Journal:  Proc AMIA Symp       Date:  2002

Review 4.  Computational dosimetry and treatment planning considerations for neutron capture therapy.

Authors:  David W Nigg
Journal:  J Neurooncol       Date:  2003 Mar-Apr       Impact factor: 4.130

Review 5.  The use of medical images in planning and delivery of radiation therapy.

Authors:  I J Kalet; M M Austin-Seymour
Journal:  J Am Med Inform Assoc       Date:  1997 Sep-Oct       Impact factor: 4.497

6.  A hierarchical evolutionary algorithm for multiobjective optimization in IMRT.

Authors:  Clay Holdsworth; Minsun Kim; Jay Liao; Mark H Phillips
Journal:  Med Phys       Date:  2010-09       Impact factor: 4.071

7.  Two-step intensity modulated arc therapy (2-step IMAT) with segment weight and width optimization.

Authors:  Jidi Sun; Theam Yong Chew; Juergen Meyer
Journal:  Radiat Oncol       Date:  2011-06-02       Impact factor: 3.481

8.  Validation of the Pinnacle³ photon convolution-superposition algorithm applied to fast neutron beams.

Authors:  Alan M Kalet; George A Sandison; Mark H Phillips; Upendra Parvathaneni
Journal:  J Appl Clin Med Phys       Date:  2013-11-04       Impact factor: 2.102

9.  Use of intensity modulation for missing tissue compensation of pediatric spinal fields.

Authors:  M H Phillips; P S Cho; H Parsai; J G Douglas
Journal:  J Appl Clin Med Phys       Date:  2003       Impact factor: 2.102

10.  Identification of the group IIa WRKY subfamily and the functional analysis of GhWRKY17 in upland cotton (Gossypium hirsutum L.).

Authors:  Lijiao Gu; Libei Li; Hengling Wei; Hantao Wang; Junji Su; Yaning Guo; Shuxun Yu
Journal:  PLoS One       Date:  2018-01-25       Impact factor: 3.240

  10 in total

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