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Literature DB >> 8891791

2,5-Hexanedione induced apoptosis in cultured mouse DRG neurons.

Y Ogawa¹, H Shimizu, S U Kim.

Abstract

Entities: Chemical Species

Mesh：

Substances：
Hexanones
2,5-hexanedione

Year: 1996 PMID： 8891791 DOI： 10.1007/bf00377875

Source DB: PubMed Journal: Int Arch Occup Environ Health ISSN： 0340-0131 Impact factor: 3.015

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13 in total

1. Characterization of the metabolites of methyl n-butyl ketone, methyl iso-butyl ketone, and methyl ethyl ketone in guinea pig serum and their clearance.

Authors: G D DiVincenzo; C J Kaplan; J Dedinas
Journal: Toxicol Appl Pharmacol Date: 1976-06 Impact factor: 4.219

2. Comparative neurotoxicity and pyrrole-forming potential of 2,5-hexanedione and perdeuterio-2,5-hexanedione in the rat.

Authors: A P DeCaprio; R G Briggs; S J Jackowski; J C Kim
Journal: Toxicol Appl Pharmacol Date: 1988-01 Impact factor: 4.219

3. Biotransformation of n-hexane and methyl n-butyl ketone in guinea pigs and mice.

Authors: D Couri; M S Abdel-Rahman; L B Hetland
Journal: Am Ind Hyg Assoc J Date: 1978-04

4. The relative neurotoxicity of methyl-n-butyl ketone, n-hexane and their metabolites.

Authors: W J Krasavage; J L O'Donoghue; G D DiVincenzo; C J Terhaar
Journal: Toxicol Appl Pharmacol Date: 1980-03-15 Impact factor: 4.219

5. Experimental neuropathy produced by 2,5-hexanedione--a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone.

Authors: P S Spencer; H H Schaumburg
Journal: J Neurol Neurosurg Psychiatry Date: 1975-08 Impact factor: 10.154

6. In vitro evidence that covalent crosslinking of neurofilaments occurs in gamma-diketone neuropathy.

Authors: D G Graham; G Szakál-Quin; J W Priest; D C Anthony
Journal: Proc Natl Acad Sci U S A Date: 1984-08 Impact factor: 11.205

7. Uncoupling of cerebral glucose supply and utilization after hexane-2,5-dione intoxication in the rat.

Authors: A M Planas; V J Cunningham
Journal: J Neurochem Date: 1987-03 Impact factor: 5.372

8. Alterations in rat axonal cytoskeletal proteins induced by in vitro and in vivo 2,5-hexanedione exposure.

Authors: A P DeCaprio; E A O'Neill
Journal: Toxicol Appl Pharmacol Date: 1985-04 Impact factor: 4.219

9. Toxic polyneuropathy produced by methyl N-butyl ketone.

Authors: J R Mendell; K Saida; M F Ganansia; D B Jackson; H Weiss; R W Gardier; C Chrisman; N Allen; D Couri; J O'Neill; B Marks; L Hetland
Journal: Science Date: 1974-08-30 Impact factor: 47.728

10. 2,5-Hexanedione is a potent gliatoxin in in-vitro cell cultures of the nervous system.

Authors: F Boegner; W Grüning; G Stoltenburg-Didinger; P Marx; H Altenkirch
Journal: Neurotoxicology Date: 1992 Impact factor: 4.294

7 in total

1. Expression of Bcl-2, Bax and Caspase-3 in nerve tissues of rats chronically exposed to 2,5-hexanedione.

Authors: Ning Cui; Shanxia Li; Xiulan Zhao; Tianliang Zhang; Cuili Zhang; Lihua Yu; Zhengping Zhu; Keqin Xie
Journal: Neurochem Res Date: 2007-05-11 Impact factor: 3.996

2. 2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway.

Authors: Ruolin Chen; Shuang Liu; Fengyuan Piao; Zhemin Wang; Yuan Qi; Shuangyue Li; Dongmei Zhang; Jingshun Shen
Journal: Ind Health Date: 2015-01-29 Impact factor: 2.179

3. Bone marrow mesenchymal stem cells attenuate 2,5-hexanedione-induced neuronal apoptosis through a NGF/AKT-dependent pathway.

Authors: Qingshan Wang; Guohua Sun; Chenxue Gao; Lina Feng; Yan Zhang; Jie Hao; Enjun Zuo; Cong Zhang; Shuangyue Li; Fengyuan Piao
Journal: Sci Rep Date: 2016-10-05 Impact factor: 4.379

4. 2,5-hexanedione downregulates nerve growth factor and induces neuron apoptosis in the spinal cord of rats via inhibition of the PI3K/Akt signaling pathway.

Authors: Zhemin Wang; Zewen Qiu; Chenxue Gao; Yijie Sun; Wei Dong; Yan Zhang; Ruolin Chen; Yuan Qi; Shuangyue Li; Yanjie Guo; Yongjun Piao; Sheng Li; Fengyuan Piao
Journal: PLoS One Date: 2017-06-27 Impact factor: 3.240