Literature DB >> 8890672

Does major depression result in lasting personality change?

M T Shea1, A C Leon, T I Mueller, D A Solomon, M G Warshaw, M B Keller.   

Abstract

OBJECTIVE: Individuals with a history of depression are characterized by high levels of certain personality traits, particularly neuroticism, introversion, and interpersonal dependency. The authors examined the "scar hypothesis," i.e., the possibility that episodes of major depression result in lasting personality changes that persist beyond recovery from the depression.
METHOD: A large sample of first-degree relatives, spouses, and comparison subjects ascertained in connection with the proband sample from the National Institute of Mental Health Collaborative Program on the Psychobiology of Depression were assessed at two points in time separated by an interval of 6 years. Subjects with a prospectively observed first episode of major depression during the interval were compared with subjects remaining well in terms of change from time 1 to time 2 in self-reported personality traits. All subjects studied were well (had no mental disorders) at the time of both assessments.
RESULTS: There was no evidence of negative change from premorbid to postmorbid assessment in any of the personality traits for subjects with a prospectively observed first episode of major depression during the interval. The results suggested a possible association of number and length of episodes with increased levels of emotional reliance and introversion, respectively.
CONCLUSIONS: The findings suggest that self-reported personality traits do not change after a typical episode of major depression. Future studies are needed to determine whether such change occurs following more severe, chronic, or recurrent episodes of depression.

Entities:  

Mesh:

Year:  1996        PMID: 8890672     DOI: 10.1176/ajp.153.11.1404

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  23 in total

1.  Assessment of subclinical symptoms and psychological well-being in depression.

Authors:  G A Fava; L Mangelli
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2001       Impact factor: 5.270

2.  The impact of comorbid dysthymic disorder on outcome in personality disorders.

Authors:  David J Hellerstein; Andrew E Skodol; Eva Petkova; Hui Xie; John C Markowitz; Shirley Yen; John Gunderson; Carlos Grilo; Maria T Daversa; Thomas H McGlashan
Journal:  Compr Psychiatry       Date:  2010-01-08       Impact factor: 3.735

3.  EXPLORING PERSONALITY DIAGNOSIS STABILITY FOLLOWING ACUTE PSYCHOTHERAPY FOR CHRONIC POSTTRAUMATIC STRESS DISORDER.

Authors:  John C Markowitz; Eva Petkova; Tatyana Biyanova; Ke Ding; Eun Jung Suh; Yuval Neria
Journal:  Depress Anxiety       Date:  2015-10-06       Impact factor: 6.505

Review 4.  Risk for recurrence in depression.

Authors:  Stephanie L Burcusa; William G Iacono
Journal:  Clin Psychol Rev       Date:  2007-03-03

5.  Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples.

Authors:  Kenneth S Kendler; Charles O Gardner; Michael C Neale; Steve Aggen; Andrew Heath; Lucía Colodro-Conde; Baptiste Couvyduchesne; Enda M Byrne; Nicholas G Martin; Nathan A Gillespie
Journal:  Psychol Med       Date:  2018-12-19       Impact factor: 7.723

Review 6.  Temperament and its role in developmental psychopathology.

Authors:  David C Rettew; Laura McKee
Journal:  Harv Rev Psychiatry       Date:  2005 Jan-Feb       Impact factor: 3.732

Review 7.  Personality and depression: explanatory models and review of the evidence.

Authors:  Daniel N Klein; Roman Kotov; Sara J Bufferd
Journal:  Annu Rev Clin Psychol       Date:  2011       Impact factor: 18.561

Review 8.  Prevalence and outcome of partial remission in depression.

Authors:  Richard Tranter; Claire O'Donovan; Praful Chandarana; Sidney Kennedy
Journal:  J Psychiatry Neurosci       Date:  2002-07       Impact factor: 6.186

9.  Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?

Authors:  Alexandre Y Dombrovski; Jill M Cyranowski; Benoit H Mulsant; Patricia R Houck; Daniel J Buysse; Carmen Andreescu; Michael E Thase; Alan G Mallinger; Ellen Frank
Journal:  Depress Anxiety       Date:  2008       Impact factor: 6.505

Review 10.  Neuroticism and common mental disorders: meaning and utility of a complex relationship.

Authors:  Bertus F Jeronimus; Roman Kotov; Johan Ormel; Harriëtte Riese; Elisabeth H Bos; Benjamin Hankin; Judith G M Rosmalen; Albertine J Oldehinkel
Journal:  Clin Psychol Rev       Date:  2013-04-29
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