OBJECTIVE: To examine the effect of a relatively low dose of creatine on skeletal muscle metabolism and oxygen supply in a group of training athletes. METHODS:31P magnetic resonance and near-infrared spectroscopy were used to study calf muscle metabolism in a group of 10 female members of a university swimming team. Studies were performed before and after a six week period of training during which they took either 2 g creatine daily or placebo. Calf muscle metabolism and creatine/choline ratios were studied in resting muscle, during plantar flexion exercise (10-15 min), and during recovery from exercise. RESULTS: There was no effect of creatine on metabolite ratios at rest or on metabolism during exercise and recovery from exercise. Muscle oxygen supply and exercise performance were not improved by creatine if compared to placebo treated subjects. CONCLUSIONS:Oral creatine supplementation at 2 g daily has no effect on muscle creatine concentration, muscle oxygen supply or muscle aerobic or anaerobic metabolism during endurance exercise.
RCT Entities:
OBJECTIVE: To examine the effect of a relatively low dose of creatine on skeletal muscle metabolism and oxygen supply in a group of training athletes. METHODS: 31P magnetic resonance and near-infrared spectroscopy were used to study calf muscle metabolism in a group of 10 female members of a university swimming team. Studies were performed before and after a six week period of training during which they took either 2 g creatine daily or placebo. Calf muscle metabolism and creatine/choline ratios were studied in resting muscle, during plantar flexion exercise (10-15 min), and during recovery from exercise. RESULTS: There was no effect of creatine on metabolite ratios at rest or on metabolism during exercise and recovery from exercise. Muscle oxygen supply and exercise performance were not improved by creatine if compared to placebo treated subjects. CONCLUSIONS: Oral creatine supplementation at 2 g daily has no effect on muscle creatine concentration, muscle oxygen supply or muscle aerobic or anaerobic metabolism during endurance exercise.
Authors: M J Peral; M García-Delgado; M L Calonge; J M Durán; M C De La Horra; T Wallimann; O Speer; A Ilundáin Journal: J Physiol Date: 2002-11-15 Impact factor: 5.182
Authors: José L M Mesa; Jonatan R Ruiz; M Marcela González-Gross; Angel Gutiérrez Sáinz; Manuel J Castillo Garzón Journal: Sports Med Date: 2002 Impact factor: 11.136
Authors: Elaine C Lee; Carl M Maresh; William J Kraemer; Linda M Yamamoto; Disa L Hatfield; Brooke L Bailey; Lawrence E Armstrong; Jeff S Volek; Brendon P McDermott; Stuart As Craig Journal: J Int Soc Sports Nutr Date: 2010-07-19 Impact factor: 5.150
Authors: Irlena M W Moura; Fernando Farias Dos Santos; José A A Moura; Rui Curi; Luiz C Fernandes Journal: J Sports Sci Med Date: 2002-09-01 Impact factor: 2.988