PURPOSE: To evaluate the use of orally administered water as a negative contrast agent and intravenously administered glucagon in helical computed tomography (CT) of the upper abdomen. MATERIALS AND METHODS: Ninety-eight adult patients underwent 102 helical CT examinations. Patients received 700 mL of water orally 30 minutes before and another 350 mL of water orally with 1 mg of glucagon intravenously just before CT. The amount of water actually ingested was recorded. Luminal distention at five sites was graded on a three-point scale; depiction of six normal anatomic structures was evaluated. RESULTS: Luminal distention improved with the amount of water ingested in four of the five sites (P < .03 in three sites). Depiction of all six normal anatomic structures improved with increasing luminal distention (P < .001). The normal duodenal papilla was seen in 42% (83 of 198) of the examinations. Of 87 patients who had previously undergone CT with positive oral contrast agents, 89% (n = 77) preferred the water, 11% (n = 10) had no preference, and none preferred the positive agent (P < .001). Upper gastrointestinal tract abnormalities were easily recognized and depicted. CONCLUSION: Water is an efficacious negative contrast agent for evaluation of the upper gastrointestinal tract during helical CT.
PURPOSE: To evaluate the use of orally administered water as a negative contrast agent and intravenously administered glucagon in helical computed tomography (CT) of the upper abdomen. MATERIALS AND METHODS: Ninety-eight adult patients underwent 102 helical CT examinations. Patients received 700 mL of water orally 30 minutes before and another 350 mL of water orally with 1 mg of glucagon intravenously just before CT. The amount of water actually ingested was recorded. Luminal distention at five sites was graded on a three-point scale; depiction of six normal anatomic structures was evaluated. RESULTS: Luminal distention improved with the amount of water ingested in four of the five sites (P < .03 in three sites). Depiction of all six normal anatomic structures improved with increasing luminal distention (P < .001). The normal duodenal papilla was seen in 42% (83 of 198) of the examinations. Of 87 patients who had previously undergone CT with positive oral contrast agents, 89% (n = 77) preferred the water, 11% (n = 10) had no preference, and none preferred the positive agent (P < .001). Upper gastrointestinal tract abnormalities were easily recognized and depicted. CONCLUSION:Water is an efficacious negative contrast agent for evaluation of the upper gastrointestinal tract during helical CT.
Authors: Vahid Yaghmai; Anahita Aghaei-Lasboo; Warren M Brandwein; Sandra Tochetto; John N Mafi; Frank H Miller; Paul Nikolaidis Journal: Emerg Radiol Date: 2010-08-04
Authors: Ahmed Ba-Ssalamah; Wolfgang Matzek; Susanne Baroud; Nina Bastati; Johannes Zacherl; Sebastian F Schoppmann; Michael Hejna; Fritz Wrba; Michael Weber; Christian J Herold; Richard M Gore Journal: Eur Radiol Date: 2011-06-28 Impact factor: 5.315
Authors: Ralph Berther; Michael A Patak; Boris Eckhardt; Sukru M Erturk; Christoph L Zollikofer Journal: Eur Radiol Date: 2008-04-15 Impact factor: 5.315
Authors: Michael A Blake; Bindu N Setty; Carmel G Cronin; Mannudeep Kalra; Nagaraj Setty Holalkere; Alan J Fischman; Peter R Mueller; Dushyant V Sahani Journal: Eur Radiol Date: 2009-08-13 Impact factor: 5.315